Meclizine and Pazeo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Meclizine (meclizine hydrochloride) and Pazeo (olopatadine hydrochloride). Common drug interactions include maculopathy among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Meclizine and Pazeo. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Meclizine?

Meclizine has active ingredients of meclizine hydrochloride. It is often used in dizziness. eHealthMe is studying from 23,117 Meclizine users. Check the latest studies of Meclizine.

What is Pazeo?

Pazeo has active ingredients of olopatadine hydrochloride. eHealthMe is studying from 1,256 Pazeo users. Check the latest studies of Pazeo.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

24 people who take Meclizine and Pazeo together, and have interactions are studied.

What are the common drug interactions of Meclizine and Pazeo, by gender? *:

female:

Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Anxiety
Headache (pain in head)
Somnolence (a state of near-sleep, a strong desire for sleep)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthma
Chronic kidney disease
Depression
Knee arthroplasty

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Pancreatitis (inflammation of pancreas)
Panic attack
Vomiting
Drug ineffective
Renal failure (kidney dysfunction)
Emotional distress
Pain
Chronic kidney disease

What are the common drug interactions of Meclizine and Pazeo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Pain
Headache (pain in head)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Somnolence (a state of near-sleep, a strong desire for sleep)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthma
Dehydration (dryness resulting from the removal of water)
Diarrhoea

50-59:

Panic attack
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal failure (kidney dysfunction)
Renal hypertension (high blood pressure caused by the kidneys hormonal response)
Chronic kidney disease
Depression
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Multiple injuries

60+:

Drug ineffective
Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

Hiv Infection: 8 people, 33.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 25.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 25.00%
High Blood Cholesterol: 6 people, 25.00%
Hypersensitivity: 6 people, 25.00%
Migraine (headache): 5 people, 20.83%
Cystitis Interstitial (unknown cause characterized by bladder pain): 4 people, 16.67%
Depression: 4 people, 16.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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