Medrol and Calan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Medrol (methylprednisolone) and Calan (verapamil hydrochloride). Common drug interactions include hyperdynamic left ventricle among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Medrol and Calan. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Medrol?

Medrol has active ingredients of methylprednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 24,443 Medrol users. Check the latest studies of Medrol.

What is Calan?

Calan has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 3,916 Calan users. Check the latest studies of Calan.



On Jul, 14, 2026

24 people who take Medrol and Calan together, and have interactions are studied.

Medrol and Calan drug interactions.

What are the common drug interactions of Medrol and Calan, by gender? *:

female:

  1. Hyperdynamic left ventricle
  2. Hyperhidrosis (abnormally increased sweating)
  3. Hypersensitivity
  4. Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins)
  5. Influenza
  6. International normalised ratio increased
  7. Intra-abdominal haematoma (intra-abdominal localized swelling filled with blood)
  8. Loss of consciousness
  9. Lymphadenopathy (disease or enlargement of lymph nodes)
  10. Metastases to lung (cancer spreads to lung)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Pneumonia
  3. Cardiac enzymes increased
  4. Chronic kidney disease
  5. Chronic obstructive airways disease
  6. Cough
  7. Decreased appetite
  8. Dehydration (dryness resulting from the removal of water)
  9. Electrocardiogram abnormal
  10. Haematocrit decreased

What are the common drug interactions of Medrol and Calan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

40-49:

  1. Hepatocellular damage (liver damage)

50-59:

  1. Hypersensitivity
  2. Influenza
  3. Lymphadenopathy (disease or enlargement of lymph nodes)
  4. Metastases to lung (cancer spreads to lung)
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Oropharyngeal pain
  7. Oxygen saturation decreased
  8. Pyrexia (fever)
  9. Rash
  10. Rash pruritic (redness with itching)

60+:

  1. Depression
  2. Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
  3. Nausea (feeling of having an urge to vomit)
  4. Colitis (inflammation of colon)
  5. Death
  6. Hyperlipidaemia (presence of excess lipids in the blood)
  7. Hypokalaemia (low potassium)
  8. Abdominal discomfort
  9. Adverse event
  10. Asthma

What are the existing conditions these people have? *

  1. Oedema Peripheral (superficial swelling): 6 people, 25.00%
  2. Lung Cancer - Non-Small Cell (lung cancer): 6 people, 25.00%
  3. Pain: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Medrol and Calan?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Medrol and Calan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Calan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Medrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Calan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone and verapamil hydrochloride (the active ingredients of Medrol and Calan, respectively), and Medrol and Calan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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