Medroxyprogesterone acetate and Arava drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Medroxyprogesterone acetate (medroxyprogesterone acetate) and Arava (leflunomide). Common drug interactions include breast cancer female among females.

The phase IV clinical study analyzes what interactions people have when they take Medroxyprogesterone acetate and Arava. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Medroxyprogesterone acetate?

Medroxyprogesterone acetate has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 12,600 Medroxyprogesterone acetate users. Check the latest studies of Medroxyprogesterone acetate.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,040 Arava users. Check the latest studies of Arava.

On Jul, 27, 2026

27 people who take Medroxyprogesterone acetate and Arava together, and have interactions are studied.

Medroxyprogesterone acetate and Arava drug interactions.

What are the common drug interactions of Medroxyprogesterone Acetate and Arava, by gender? *:

female:

Breast cancer female
Depression
Hepatitis (inflammation of the liver)
Aortic valve stenosis (narrowing of the aortic valve)
Asthenia (weakness)
Deformity (disfigurement)
Pain in extremity
Dyspnoea (difficult or laboured respiration)
Allergy to animal
Anaphylactic reaction (serious allergic reaction)

male:

n/a

What are the common drug interactions of Medroxyprogesterone Acetate and Arava, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abortion spontaneous (naturally occurring miscarriage)
Drug exposure during pregnancy

30-39:

Allergy to animal
Anaphylactic reaction (serious allergic reaction)
Angioedema (rapid swelling of the dermis)
Aphonia (inability to produce voice)
Arthralgia (joint pain)
Blood pressure diastolic increased
Blood pressure increased
Blood pressure systolic increased
Chest discomfort
Dysphonia (speech disorder attributable to a disorder of phonation)

40-49:

Breast cancer female
Oedema (fluid collection in tissue)
Pruritus (severe itching of the skin)
Rash pustular (redness with pustules)
Skin burning sensation

50-59:

Breast tenderness
Drug ineffective
Cough
Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Hypoxia (low oxygen in tissues)
Oedema (fluid collection in tissue)
Pneumonia
Pyrexia (fever)
Silicosis (a lung disease that is caused by inhaling tiny bits of silica)

60+:

Breast cancer female
Depression
Aortic valve stenosis (narrowing of the aortic valve)
Asthenia (weakness)
Deformity (disfigurement)
Pain in extremity
Fatigue (feeling of tiredness)
Breast cancer
Carotid artery stenosis (narrowing of carotid artery)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 18.52%

* Approximation only. Some reports may have incomplete information.

Do you take Medroxyprogesterone acetate and Arava?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously