Mefenamic acid and Gravol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mefenamic acid (mefenamic acid) and Gravol (dimenhydrinate). Common drug interactions include red blood cell elliptocytes present among females and alcohol use among males.

The phase IV clinical study analyzes what interactions people have when they take Mefenamic acid and Gravol. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Mefenamic acid?

Mefenamic acid has active ingredients of mefenamic acid. It is often used in painful menstrual periods. eHealthMe is studying from 4,844 Mefenamic acid users. Check the latest studies of Mefenamic acid.

What is Gravol?

Gravol has active ingredients of dimenhydrinate. It is often used in nausea. eHealthMe is studying from 7,193 Gravol users. Check the latest studies of Gravol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

64 people who take Mefenamic acid and Gravol together, and have interactions are studied.

Mefenamic acid and Gravol drug interactions.

What are the common drug interactions of Mefenamic Acid and Gravol, by gender? *:

female:

Red blood cell elliptocytes present
Sinus congestion (blockage of sinus)
Headache (pain in head)
Dizziness
Fatigue (feeling of tiredness)
Discomfort
Hypotension (abnormally low blood pressure)
Disturbance in attention
Drug intolerance (drug sensitivity)
Mastoiditis (infection of mastoid bone)

male:

Alcohol use
Balance disorder
Restlessness (not able to rest)
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight decreased
Chest injury
Cough
Decreased appetite
Dependence
Fall

What are the common drug interactions of Mefenamic Acid and Gravol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Headache (pain in head)
Lymphocyte count decreased
Pruritus (severe itching of the skin)
Rash
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Hypertension (high blood pressure)
Bacterial test positive
Blood urine present

40-49:

Neutropenia (an abnormally low number of neutrophils)
Peripheral swelling
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Photosensitivity reaction
Pulmonary congestion (congestion in the lungs)
Red blood cell count decreased
Red blood cell elliptocytes present
Sinus congestion (blockage of sinus)
Sinus pain
Sinusitis (inflammation of sinus)

50-59:

Abdominal pain upper
Chills (felling of cold)
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal pain
Hyperhidrosis (abnormally increased sweating)
Abdominal distension
Drug ineffective
Dry eye (lack of adequate tears)
Dry mouth

60+:

Abdominal pain upper
Anal haemorrhage
Diarrhoea
Dizziness
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Eye haemorrhage (bleeding in the eye)
Eye irritation
Fall
Headache (pain in head)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)

What are the existing conditions these people have? *

Migraine (headache): 31 people, 48.44%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 15 people, 23.44%
Headache (pain in head): 14 people, 21.88%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 7.81%
Oral Herpes (viral infection of mouth): 5 people, 7.81%
Neuralgia (pain in one or more nerves): 5 people, 7.81%
Fever: 5 people, 7.81%
Antiphospholipid Antibodies Positive: 4 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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