Megace es and Zometa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Megace es (megestrol acetate) and Zometa (zoledronic acid). Common drug interactions include hip fracture among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Megace es and Zometa. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Megace es?

Megace es has active ingredients of megestrol acetate. eHealthMe is studying from 611 Megace es users. Check the latest studies of Megace es.

What is Zometa?

Zometa has active ingredients of zoledronic acid. It is often used in multiple myeloma. eHealthMe is studying from 71,434 Zometa users. Check the latest studies of Zometa.

On Jul, 09, 2026

21 people who take Megace es and Zometa together, and have interactions are studied.

What are the common drug interactions of Megace Es and Zometa, by gender? *:

female:

Hip fracture
Lethargy (tiredness)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Muscular weakness (muscle weakness)
Adverse event
Aphagia (inability or refusal to swallow)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Bone pain
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

male:

Dehydration (dryness resulting from the removal of water)
Hypotension (abnormally low blood pressure)
Vomiting
Abdominal pain
Acute respiratory failure
Blood potassium decreased
Decreased appetite
Dermatitis allergic (inflammation of the skin due allergic reaction)
Dry skin
Erythema (redness of the skin)

What are the common drug interactions of Megace Es and Zometa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Dehydration (dryness resulting from the removal of water)
Hypotension (abnormally low blood pressure)
Lethargy (tiredness)
Malignant neoplasm progression (cancer tumour came back)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Muscular weakness (muscle weakness)
Renal failure acute (rapid kidney dysfunction)
Vomiting
Abdominal pain
Acute respiratory failure

What are the existing conditions these people have? *

Pain: 4 people, 19.05%
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 3 people, 14.29%
Lung Cancer - Non-Small Cell (lung cancer): 3 people, 14.29%
High Blood Pressure: 3 people, 14.29%
Weight Decreased: 2 people, 9.52%
High Blood Cholesterol: 2 people, 9.52%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 9.52%
Chest Pain: 2 people, 9.52%
Constipation: 2 people, 9.52%
Cough: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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