Megace and Camptosar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Megace (megestrol acetate) and Camptosar (irinotecan hydrochloride). Common drug interactions include dysphagia among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Megace and Camptosar. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Megace?

Megace has active ingredients of megestrol acetate. It is often used in weight loss. eHealthMe is studying from 10,095 Megace users. Check the latest studies of Megace.

What is Camptosar?

Camptosar has active ingredients of irinotecan hydrochloride. eHealthMe is studying from 7,145 Camptosar users. Check the latest studies of Camptosar.

On Jul, 21, 2026

64 people who take Megace and Camptosar together, and have interactions are studied.

What are the common drug interactions of Megace and Camptosar, by gender? *:

female:

Dysphagia (a condition in which swallowing is difficult or painful)
Febrile neutropenia (fever with reduced white blood cells)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Respiratory failure (inadequate gas exchange by the respiratory system)
Hypokalaemia (low potassium)
Influenza
Multi-organ failure (multisystem organ failure)
Septic shock (shock due to blood infection)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

male:

Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Vomiting
Pyrexia (fever)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Dyspepsia (indigestion)
Dysphagia (a condition in which swallowing is difficult or painful)
Haematocrit decreased
Hyperkalaemia (damage to or disease of the kidney)
Hypokalaemia (low potassium)

What are the common drug interactions of Megace and Camptosar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Acne (skin problems that cause pimples)
Dry skin
Hypoaesthesia (reduced sense of touch or sensation)

40-49:

Dehydration (dryness resulting from the removal of water)
Abdominal distension
Abdominal pain
Abdominal pain lower
Asthenia (weakness)
Back pain
Breath sounds
Chest discomfort
Cough
Death

50-59:

Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Back pain
Dehydration (dryness resulting from the removal of water)
Dry mouth
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Haematocrit decreased
Heart rate increased
Hypokalaemia (low potassium)

60+:

Diarrhoea
Dehydration (dryness resulting from the removal of water)
Renal failure acute (rapid kidney dysfunction)
Vomiting
Febrile neutropenia (fever with reduced white blood cells)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Respiratory failure (inadequate gas exchange by the respiratory system)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Hyperkalaemia (damage to or disease of the kidney)

What are the existing conditions these people have? *

Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 9 people, 14.06%
Colon Cancer: 7 people, 10.94%
High Blood Pressure: 5 people, 7.81%
High Blood Cholesterol: 5 people, 7.81%
Diabetes: 5 people, 7.81%
Colon Cancer Metastatic (cancer of colon spreads to other part of body): 5 people, 7.81%

* Approximation only. Some reports may have incomplete information.

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