Megace and Detrol la drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Megace (megestrol acetate) and Detrol la (tolterodine tartrate). Common drug interactions include colon cancer among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Megace and Detrol la. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Megace?

Megace has active ingredients of megestrol acetate. It is often used in weight loss. eHealthMe is studying from 10,095 Megace users. Check the latest studies of Megace.

What is Detrol la?

Detrol la has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 13,358 Detrol la users. Check the latest studies of Detrol la.

On Jul, 07, 2026

22 people who take Megace and Detrol la together, and have interactions are studied.

What are the common drug interactions of Megace and Detrol La, by gender? *:

female:

Colon cancer
Coma (state of unconsciousness lasting more than six hours)
Confusion
Diarrhoea
Drug ineffective
Dry eye (lack of adequate tears)
Dyspnoea (difficult or laboured respiration)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hepatic neoplasm malignant (liver cancer)
Hepatomegaly (abnormal enlargement of the liver)

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Rash
Abdominal pain
Alanine aminotransferase increased
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Arrhythmia supraventricular (irregular heartbeat supraventricular origin)

What are the common drug interactions of Megace and Detrol La, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal distension
Acidosis (build-up of carbon dioxide in the blood)
Confusion
Diarrhoea
Hepatomegaly (abnormal enlargement of the liver)
Hypokalaemia (low potassium)
Metastases to liver (cancer spreads to liver)
Oedema lower limb (fluid collection in tissue of lower leg)
Pain
Performance status decreased

40-49:

n/a

50-59:

n/a

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Malignant neoplasm progression (cancer tumour came back)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Rash
Abdominal pain
Acute myocardial infarction (acute heart attack)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Alanine aminotransferase increased
Anaemia (lack of blood)

What are the existing conditions these people have? *

Stress And Anxiety: 6 people, 27.27%
Platelet Aggregation Abnormal: 6 people, 27.27%
Lipids Increased (excess lipid in body): 6 people, 27.27%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 6 people, 27.27%
High Blood Pressure: 6 people, 27.27%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 27.27%
Fungal Infection: 6 people, 27.27%
Fluid Overload (too much fluid in the blood): 6 people, 27.27%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 6 people, 27.27%
Bladder Disorder: 6 people, 27.27%

* Approximation only. Some reports may have incomplete information.

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