Megace and Isordil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Megace (megestrol acetate) and Isordil (isosorbide dinitrate). Common drug interactions include colonic polyp among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Megace and Isordil. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Megace?

Megace has active ingredients of megestrol acetate. It is often used in weight loss. eHealthMe is studying from 10,095 Megace users. Check the latest studies of Megace.

What is Isordil?

Isordil has active ingredients of isosorbide dinitrate. eHealthMe is studying from 3,022 Isordil users. Check the latest studies of Isordil.

On Jul, 07, 2026

19 people who take Megace and Isordil together, and have interactions are studied.

What are the common drug interactions of Megace and Isordil, by gender? *:

female:

Colonic polyp (extra part of colon tissue grow in intestine)
Confusional state
Conjunctivitis (pink eye)
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery thrombosis (clot formation in coronary artery)
Cough
Cystitis glandularis (forming a timorous lesion with blueberry spots in the urinary bladder)
Deafness
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Constipation
Dysarthria (speech disorder)
Glossodynia (a burning or painful sensation in the tongue)
Hepatitis acute
Hyperkalaemia (damage to or disease of the kidney)
Hypotension (abnormally low blood pressure)
Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Megace and Isordil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Conjunctivitis (pink eye)
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery thrombosis (clot formation in coronary artery)
Cough
Cystitis glandularis (forming a timorous lesion with blueberry spots in the urinary bladder)
Deafness
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Depression

50-59:

Insomnia (sleeplessness)

60+:

Urinary tract infection
Lethargy (tiredness)
Coma (state of unconsciousness lasting more than six hours)
Confusional state
Constipation
Dehydration (dryness resulting from the removal of water)
Dysarthria (speech disorder)
Glossodynia (a burning or painful sensation in the tongue)
Hepatitis acute
Hyperkalaemia (damage to or disease of the kidney)

What are the existing conditions these people have? *

Cough: 4 people, 21.05%
Sleep Disorder: 3 people, 15.79%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 15.79%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 15.79%
Insomnia (sleeplessness): 3 people, 15.79%
High Blood Pressure: 3 people, 15.79%
Abdominal Pain Upper: 3 people, 15.79%
Multiple Myeloma (cancer of the plasma cells): 2 people, 10.53%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 10.53%
Pulmonary Congestion (congestion in the lungs): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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