Megace and Lovastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Megace (megestrol acetate) and Lovastatin (lovastatin). Common drug interactions include dyspnoea among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Megace and Lovastatin. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Megace?

Megace has active ingredients of megestrol acetate. It is often used in weight loss. eHealthMe is studying from 10,095 Megace users. Check the latest studies of Megace.

What is Lovastatin?

Lovastatin has active ingredients of lovastatin. It is often used in high blood cholesterol. eHealthMe is studying from 33,048 Lovastatin users. Check the latest studies of Lovastatin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 13, 2026

76 people who take Megace and Lovastatin together, and have interactions are studied.

Megace and Lovastatin drug interactions.

What are the common drug interactions of Megace and Lovastatin, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Fall
Osteonecrosis of jaw (death of bone of jaw)
Pain
Anxiety
Constipation
Depression
Dysuria (painful or difficult urination)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypokalaemia (low potassium)

male:

Constipation
Pain
Disturbance in attention
Haemoglobin decreased
Melaena (the passage of black, tarry stools)
Peripheral swelling
Rectal haemorrhage (bleeding from anus)
Renal failure acute (rapid kidney dysfunction)
Blood glucose increased
Cardiac failure congestive

What are the common drug interactions of Megace and Lovastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Acute myocardial infarction (acute heart attack)
Nausea (feeling of having an urge to vomit)
Pain
Bone disorder
Injection site discolouration
Injection site induration
Injection site reaction
Injection site swelling
Injection site urticaria (rash of round, red welts on the skin at injection site)
Nasal septum deviation (deviated nasal septum)

50-59:

Contusion (a type of hematoma of tissue in which capillaries)
Dyspnoea (difficult or laboured respiration)
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)
Hip fracture
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)
Metastases to spine (cancer spreads to spine)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)

60+:

Constipation
Dehydration (dryness resulting from the removal of water)
Pneumonia
Nausea (feeling of having an urge to vomit)
Pulmonary embolism (blockage of the main artery of the lung)
Rectal haemorrhage (bleeding from anus)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac failure congestive
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Angiodysplasia (small vascular malformation of the gut)

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 8 people, 10.53%
High Blood Pressure: 8 people, 10.53%
Nausea (feeling of having an urge to vomit): 7 people, 9.21%
Diarrhea: 6 people, 7.89%
Pain: 5 people, 6.58%
Multiple Myeloma (cancer of the plasma cells): 5 people, 6.58%
Diabetes: 5 people, 6.58%
Brain Cancer Metastatic: 5 people, 6.58%
Anaemia (lack of blood): 5 people, 6.58%
Oedema (fluid collection in tissue): 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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