Megace and Viagra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Megace (megestrol acetate) and Viagra (sildenafil citrate). Common drug interactions include blood sodium decreased among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Megace and Viagra. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Megace?

Megace has active ingredients of megestrol acetate. It is often used in weight loss. eHealthMe is studying from 10,095 Megace users. Check the latest studies of Megace.

What is Viagra?

Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.

On Jul, 15, 2026

50 people who take Megace and Viagra together, and have interactions are studied.

What are the common drug interactions of Megace and Viagra, by gender? *:

female:

Blood sodium decreased
Bone disorder
Cardiac murmur (an heart sound in valve abnormality)
Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
Chest pain
Chills (felling of cold)
Decreased interest
Dental caries
Depression
Dysuria (painful or difficult urination)

male:

Anxiety
Pain
Tooth extraction
Osteonecrosis of jaw (death of bone of jaw)
Arthralgia (joint pain)
Blood oestrogen increased
Gingival disorder (gum disease)
Hallucination, visual (seeing things that aren't there)
Hypoaesthesia (reduced sense of touch or sensation)
Jaw disorder (jaw disease)

What are the common drug interactions of Megace and Viagra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Hallucination (an experience involving the perception of something not present)
Pain
Renal failure (kidney dysfunction)

40-49:

Anxiety
Pain
Depression
Asthenia (weakness)
Bone disorder
Chest pain
Decreased interest
Dental caries
Dysuria (painful or difficult urination)
Fatigue (feeling of tiredness)

50-59:

Narcolepsy (brain's inability to regulate sleep-wake cycles normally)
Neoplasm malignant (cancer tumour)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Gait disturbance
Gastric mucosal lesion (lesion of stomach mucous membrane)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypoxia (low oxygen in tissues)
Laceration (tearing of soft body tissue)
Neutropenia (an abnormally low number of neutrophils)

60+:

Anaemia (lack of blood)
Asthenia (weakness)
Acetabulum fracture (socket of the hip joint- fracture)
Adrenal mass
Arrhythmia (irregular heartbeat)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Cardiac disorder
Cardiac failure congestive
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

Prostate Cancer: 24 people, 48.00%
Metastases To Bone (cancer spreads to bone): 14 people, 28.00%
Nausea (feeling of having an urge to vomit): 12 people, 24.00%
Weakness: 9 people, 18.00%
Hypoaesthesia (reduced sense of touch or sensation): 8 people, 16.00%
Pain: 7 people, 14.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 14.00%
Cough: 6 people, 12.00%
Dyspnea (difficult or laboured breathing): 6 people, 12.00%
High Blood Pressure: 5 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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