Megestrol acetate and Aripiprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Megestrol acetate (megestrol acetate) and Aripiprazole (aripiprazole). Common drug interactions include fatigue among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Megestrol acetate and Aripiprazole. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Megestrol acetate?

Megestrol acetate has active ingredients of megestrol acetate. It is often used in appetite - decreased. eHealthMe is studying from 5,427 Megestrol acetate users. Check the latest studies of Megestrol acetate.

What is Aripiprazole?

Aripiprazole has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 39,143 Aripiprazole users. Check the latest studies of Aripiprazole.



On Jul, 12, 2026

14 people who take Megestrol acetate and Aripiprazole together, and have interactions are studied.

Megestrol acetate and Aripiprazole drug interactions.

What are the common drug interactions of Megestrol Acetate and Aripiprazole, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Anaemia (lack of blood)
  3. Blood pressure increased
  4. Clostridium test positive
  5. Cytomegalovirus colitis (an inflammation of the colon from virus)
  6. Diarrhoea
  7. Fall
  8. Herpes zoster
  9. Hyperbilirubinaemia (excess of bilirubin in the blood)
  10. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

male:

  1. Pain
  2. Asthenia (weakness)
  3. Insomnia (sleeplessness)
  4. Nausea (feeling of having an urge to vomit)
  5. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  6. Pulmonary function test decreased
  7. Respiratory syncytial virus infection (viral disease of respiratory system)
  8. Respiratory tract congestion (blockage on respiratory system)
  9. Rhinorrhoea (watery mucus discharge from the nose)
  10. Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)

What are the common drug interactions of Megestrol Acetate and Aripiprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Calculus urethral (stone in urethra)
  2. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  3. Obstruction gastric (obstruction in stomach)
  4. Pain
  5. Pancreatitis (inflammation of pancreas)
  6. Pancreatitis acute (sudden inflammation of pancreas)
  7. Type 2 diabetes mellitus
  8. Urethral stenosis (narrowing of the urethra, may cause decreased urine output)
  9. Weight increased

60+:

  1. Diarrhoea
  2. Anaemia (lack of blood)
  3. Insomnia (sleeplessness)
  4. Nausea (feeling of having an urge to vomit)
  5. Pain
  6. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  7. Pulmonary function test decreased
  8. Respiratory syncytial virus infection (viral disease of respiratory system)
  9. Respiratory tract congestion (blockage on respiratory system)
  10. Rhinorrhoea (watery mucus discharge from the nose)

What are the existing conditions these people have? *

  1. Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 6 people, 42.86%
  2. Pain: 6 people, 42.86%
  3. Constipation: 6 people, 42.86%
  4. Asthma: 3 people, 21.43%
  5. Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 21.43%
  6. Orthostatic Hypertension (a medical condition consisting of a sudden increase in blood pressure when a person stands up): 3 people, 21.43%
  7. Complications Of Transplanted Lung: 3 people, 21.43%
  8. Loss Of Consciousness: 3 people, 21.43%
  9. Hypoglycemia (low blood sugar): 2 people, 14.29%
  10. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Megestrol acetate and Aripiprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Megestrol acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aripiprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Megestrol acetate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aripiprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on megestrol acetate and aripiprazole (the active ingredients of Megestrol acetate and Aripiprazole, respectively), and Megestrol acetate and Aripiprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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