Melatonin and Cranberry fruit drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melatonin (melatonin) and Cranberry fruit (cranberry). Common drug interactions include gastrointestinal haemorrhage among females and chills among males.

The phase IV clinical study analyzes what interactions people have when they take Melatonin and Cranberry fruit. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

What is Cranberry fruit?

Cranberry fruit has active ingredients of cranberry. It is often used in urinary tract infection. eHealthMe is studying from 162 Cranberry fruit users. Check the latest studies of Cranberry fruit.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

15 people who take Melatonin and Cranberry fruit together, and have interactions are studied.

Melatonin and Cranberry fruit drug interactions.

What are the common drug interactions of Melatonin and Cranberry Fruit, by gender? *:

female:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Influenza like illness
Abnormal dreams
Adverse drug reaction
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anger
Aphonia (inability to produce voice)
Asthenia (weakness)
Chest pain
Cold-stimulus headache (headache by cold exposure)

male:

Chills (felling of cold)
Depression
Nausea (feeling of having an urge to vomit)
Cellulitis (infection under the skin)
Herpes zoster
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Ulcer
Dizziness
Fatigue (feeling of tiredness)

What are the common drug interactions of Melatonin and Cranberry Fruit, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anger
Asthenia (weakness)
Depressed mood
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Drug ineffective
Gait disturbance
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Ill-defined disorder
Mobility decreased (ability to move is reduced)
Muscular weakness (muscle weakness)

50-59:

Chills (felling of cold)
Depression
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Abnormal dreams
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Aphonia (inability to produce voice)
Cellulitis (infection under the skin)
Cold-stimulus headache (headache by cold exposure)
Disturbance in attention

60+:

n/a

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 33.33%
Chest Pain: 2 people, 13.33%
Nausea And Vomiting: 2 people, 13.33%
Nausea (feeling of having an urge to vomit): 2 people, 13.33%
Nasal Dryness (dry nose): 2 people, 13.33%
Colon Cancer: 2 people, 13.33%
Colon Cancer Metastatic (cancer of colon spreads to other part of body): 2 people, 13.33%
Constipation: 2 people, 13.33%
Cough: 2 people, 13.33%
Immunodeficiency Common Variable: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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