Melatonin and Geodon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melatonin (melatonin) and Geodon (ziprasidone hydrochloride). Common drug interactions include deep vein thrombosis among females and amnesia among males.

The phase IV clinical study analyzes what interactions people have when they take Melatonin and Geodon. It is created by eHealthMe based on reports of 94 people who take the same drugs from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

What is Geodon?

Geodon has active ingredients of ziprasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 19,504 Geodon users. Check the latest studies of Geodon.

On Jul, 03, 2026

94 people who take Melatonin and Geodon together, and have interactions are studied.

What are the common drug interactions of Melatonin and Geodon, by gender? *:

female:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Fear
Injection site pain
Renal failure (kidney dysfunction)
Weight decreased
Weight increased
Sedation
Somnolence (a state of near-sleep, a strong desire for sleep)
Agitation (state of anxiety or nervous excitement)

male:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Head injury
Dizziness
Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Hallucination (an experience involving the perception of something not present)
Hypertension (high blood pressure)
Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Melatonin and Geodon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Agitation (state of anxiety or nervous excitement)
Consciousness fluctuating
Hallucination (an experience involving the perception of something not present)
Hyperhidrosis (abnormally increased sweating)
Lymphocyte count decreased
Monocyte count increased
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Speech disorder
Swollen tongue (swelling of tongue)

10-19:

Drug ineffective
Sedation
Somnolence (a state of near-sleep, a strong desire for sleep)
Tremor (trembling or shaking movements in one or more parts of your body)
Abnormal behaviour
Fall
Therapeutic response unexpected
Abdominal pain upper
Dizziness
Haemorrhage (bleeding)

20-29:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Head injury
Blood glucose decreased
Dizziness
Dyskinesia (abnormality or impairment of voluntary movement)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Restlessness (not able to rest)
Abdominal pain upper
Asthma exercise induced

30-39:

Anxiety
Drug ineffective
Pain
Abasia (inability to walk)
Adverse drug reaction
Arthralgia (joint pain)
Asthenia (weakness)
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Blepharospasm (any abnormal contraction or twitch of the eyelid)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

40-49:

Psychotic disorder
Rib fracture
Urticaria (rash of round, red welts on the skin that itch intensely)
Weight decreased
Malaise (a feeling of general discomfort or uneasiness)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cholecystitis chronic (long lasting infection of gallbladder)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

50-59:

Anxiety
Chronic kidney disease
Renal failure (kidney dysfunction)
Accident
Adverse drug reaction
Adverse event
Blood cholesterol increased
Blood testosterone decreased
Blood triglycerides increased
Cardiac disorder

60+:

Chronic kidney disease
Malaise (a feeling of general discomfort or uneasiness)
Disease recurrence
Fall
Hallucination (an experience involving the perception of something not present)
Head injury
Oedema peripheral (superficial swelling)
Overdose
Pneumonia
Renal disorder (kidney disease)

What are the existing conditions these people have? *

Sleep Disorder: 18 people, 19.15%
Depression: 16 people, 17.02%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 13.83%
Stress And Anxiety: 12 people, 12.77%
Pain: 10 people, 10.64%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 9.57%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 6.38%
Psoriasis (immune-mediated disease that affects the skin): 5 people, 5.32%
High Blood Cholesterol: 5 people, 5.32%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 5.32%

* Approximation only. Some reports may have incomplete information.

Do you take Melatonin and Geodon?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously