Melatonin and Increlex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melatonin (melatonin) and Increlex (mecasermin recombinant). Common drug interactions include abdominal pain upper among females and arthritis among males.

The phase IV clinical study analyzes what interactions people have when they take Melatonin and Increlex. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

What is Increlex?

Increlex has active ingredients of mecasermin recombinant. eHealthMe is studying from 1,010 Increlex users. Check the latest studies of Increlex.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

11 people who take Melatonin and Increlex together, and have interactions are studied.

Melatonin and Increlex drug interactions.

What are the common drug interactions of Melatonin and Increlex, by gender? *:

female:

Abdominal pain upper
Headache (pain in head)
Abdominal pain
Decreased appetite
Injection site mass
Injection site pain

male:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Decreased appetite
Cystic fibrosis (disease of the secretary glands)
Growth retardation (delayed growth)
Injection site extravasation (flow of (blood or lymph) from injection site)
Injection site pain
Pain
Poor quality sleep
Snoring
Viith nerve paralysis

What are the common drug interactions of Melatonin and Increlex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Decreased appetite
Drug ineffective
Restless legs syndrome (a powerful urge to move your legs)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Tonsillar hypertrophy (enlargement of the tonsils)
Abdominal pain
Injection site mass
Injection site pain
Viith nerve paralysis

10-19:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Abdominal pain upper
Viral infection
Cystic fibrosis (disease of the secretary glands)
Decreased appetite
Growth retardation (delayed growth)
Pain
Poor quality sleep
Restless legs syndrome (a powerful urge to move your legs)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 27.27%
Insulin-Like Growth Factor Decreased: 2 people, 18.18%
Growth Hormone Deficiency: 2 people, 18.18%
Body Height Below Normal: 2 people, 18.18%
Sleep Disorder: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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