Melatonin and Taltz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melatonin (melatonin) and Taltz (ixekizumab). Common drug interactions include depression among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Melatonin and Taltz. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

What is Taltz?

Taltz has active ingredients of ixekizumab. eHealthMe is studying from 29,777 Taltz users. Check the latest studies of Taltz.



On Jul, 12, 2026

21 people who take Melatonin and Taltz together, and have interactions are studied.

Melatonin and Taltz drug interactions.

What are the common drug interactions of Melatonin and Taltz, by gender? *:

female:

  1. Depression
  2. Diarrhoea
  3. Nausea (feeling of having an urge to vomit)
  4. Psoriasis (immune-mediated disease that affects the skin)
  5. Surgery
  6. Upper-airway cough syndrome
  7. Back pain
  8. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  9. Choking sensation (feeling of obstruction in respiratory system)
  10. Decreased appetite

male:

  1. Abdominal distension
  2. Cardiac failure congestive
  3. Encephalopathy (functioning of the brain is affected by some agent or condition)
  4. Erectile dysfunction
  5. Generalised oedema (swelling all over the body)
  6. Hepatic failure (liver failure)
  7. Klebsiella bacteraemia (klebsiella bacteria in blood after infection to lungs)
  8. Limb discomfort (discomfort in leg)
  9. Male orgasmic disorder (male sex satisfaction disease)
  10. Malignant melanoma (skin cancer rises from melancytes)

What are the common drug interactions of Melatonin and Taltz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Diarrhoea
  2. Dyspnoea exertional (breathlessness or shortness of breath)
  3. Pallor
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Syncope (loss of consciousness with an inability to maintain postural tone)

50-59:

  1. Colitis ulcerative (inflammation of colon with ulcer)
  2. Depression
  3. Surgery
  4. Psoriasis (immune-mediated disease that affects the skin)

60+:

  1. Abdominal distension
  2. Cardiac failure congestive
  3. Erectile dysfunction
  4. Generalised oedema (swelling all over the body)
  5. Hepatic failure (liver failure)
  6. Klebsiella bacteraemia (klebsiella bacteria in blood after infection to lungs)
  7. Lichen sclerosus (a skin disorder that causes the skin to become thin, whitened, wrinkled, and can cause itching and pain)
  8. Limb discomfort (discomfort in leg)
  9. Male orgasmic disorder (male sex satisfaction disease)
  10. Malignant melanoma (skin cancer rises from melancytes)

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 8 people, 38.10%
  2. High Blood Cholesterol: 7 people, 33.33%
  3. Gout (uric acid crystals building up in the body): 7 people, 33.33%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 33.33%
  5. Ankylosing Spondylitis (type of arthritis affecting the spine): 7 people, 33.33%
  6. High Blood Pressure: 6 people, 28.57%
  7. Cardiac Disorder: 5 people, 23.81%
  8. Cardiac Failure Congestive: 4 people, 19.05%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 14.29%
  10. Amyloidosis Senile (common form of amyloidosis in very old people, usually mild and limited to the heart): 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Melatonin and Taltz?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Melatonin and Taltz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Taltz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Melatonin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Taltz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on melatonin and ixekizumab (the active ingredients of Melatonin and Taltz, respectively), and Melatonin and Taltz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: