Melatonin and Vantin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melatonin (melatonin) and Vantin (cefpodoxime proxetil). Common drug interactions include diarrhoea among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Melatonin and Vantin. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,213 Melatonin users. Check the latest studies of Melatonin.

What is Vantin?

Vantin has active ingredients of cefpodoxime proxetil. It is often used in sinusitis. eHealthMe is studying from 788 Vantin users. Check the latest studies of Vantin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

18 people who take Melatonin and Vantin together, and have interactions are studied.

What are the common drug interactions of Melatonin and Vantin, by gender? *:

female:

Diarrhoea
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Parainfluenzae virus infection
Limb discomfort (discomfort in leg)
Altered state of consciousness (altered state of mind)
Crepitations (noises are produced by the rubbing of parts one against the other)
Discomfort
Dyspnoea (difficult or laboured respiration)
Irritability
Pneumonia

male:

Pyrexia (fever)
Abdominal discomfort
Mucosal ulceration (ulcers of mucous membrane)
Oesophagitis (inflammation of oesophagus)
Oropharyngeal pain
Abdominal distension
Enteritis (inflammation of the small intestine)
Enterococcus test positive
Enterocolitis infectious
Fatigue (feeling of tiredness)

What are the common drug interactions of Melatonin and Vantin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Aphthous ulcer (mouth ulcer)
Cytomegalovirus infection
Decreased appetite
Diarrhoea
Escherichia infection (bacterial infection by escherichia coli)
Fatigue (feeling of tiredness)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Myalgia (muscle pain)
Oedema peripheral (superficial swelling)
Pneumonia

40-49:

Altered state of consciousness (altered state of mind)
Crepitations (noises are produced by the rubbing of parts one against the other)
Discomfort
Dyspnoea (difficult or laboured respiration)
Irritability
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Rales (an abnormal respiratory sound characterized by fine crackles)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Urinary tract infection
Urinary tract infection pseudomonal

50-59:

Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Pneumonia

60+:

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Diarrhoea
Colitis (inflammation of colon)
Enteritis (inflammation of the small intestine)
Enterococcus test positive
Enterocolitis infectious
Fatigue (feeling of tiredness)
Febrile neutropenia (fever with reduced white blood cells)
Intestinal mucosal hypertrophy (enlargement of intestinal mucosa)
Lung disorder (lung disease)

What are the existing conditions these people have? *

Pain: 10 people, 55.56%
Respiratory Tract Infection: 7 people, 38.89%
Wheezing (a high-pitched whistling sound made while you breath): 6 people, 33.33%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 6 people, 33.33%
Cough: 6 people, 33.33%
Dyspnea (difficult or laboured breathing): 6 people, 33.33%
Fever: 6 people, 33.33%
Neuropathy Peripheral (surface nerve damage): 5 people, 27.78%
Type 2 Diabetes: 3 people, 16.67%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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