Mellaril and Percocet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mellaril (thioridazine hydrochloride) and Percocet (acetaminophen; oxycodone hydrochloride). Common drug interactions include amnesia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Mellaril and Percocet. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Mellaril?

Mellaril has active ingredients of thioridazine hydrochloride. eHealthMe is studying from 1,516 Mellaril users. Check the latest studies of Mellaril.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

On Jul, 28, 2026

23 people who take Mellaril and Percocet together, and have interactions are studied.

Mellaril and Percocet drug interactions.

What are the common drug interactions of Mellaril and Percocet, by gender? *:

female:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Apnoea (suspension of external breathing)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Bipolar disorder (mood disorder)
Cardiac murmur (an heart sound in valve abnormality)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest discomfort
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Confusion

male:

Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Fall
Fatigue (feeling of tiredness)
Hallucination (an experience involving the perception of something not present)
Hepatic function abnormal
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hostility
Malaise (a feeling of general discomfort or uneasiness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

What are the common drug interactions of Mellaril and Percocet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Lipase increased
Abdominal distension
Abdominal pain upper
Abnormal behaviour
Alcoholism (problems with alcohol)
Chest pain
Confusional state
Diarrhoea
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Depression
Drug dependence
Aspartate aminotransferase increased
Blood alkaline phosphatase nos increased
Blood lactate dehydrogenase increased
Cardiac murmur (an heart sound in valve abnormality)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Constipation
Death

50-59:

Eye disorder
Fall
Fibromyalgia (a long-term condition which causes pain all over the body)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Nausea (feeling of having an urge to vomit)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Spinal fracture (fracture in one of vertebrae)

60+:

Abdominal pain
Anaemia (lack of blood)
Weight decreased
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Confusion
Depressed level of consciousness
Drug ineffective
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 8.70%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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