Meloxicam and Brintellix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Meloxicam (meloxicam) and Brintellix (vortioxetine hydrobromide). Common drug interactions include scoliosis among females and chronic obstructive pulmonary disease among males.

The phase IV clinical study analyzes what interactions people have when they take Meloxicam and Brintellix. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Meloxicam?

Meloxicam has active ingredients of meloxicam. It is often used in arthritis. eHealthMe is studying from 68,016 Meloxicam users. Check the latest studies of Meloxicam.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.



On Jul, 09, 2026

67 people who take Meloxicam and Brintellix together, and have interactions are studied.

Meloxicam and Brintellix drug interactions.

What are the common drug interactions of Meloxicam and Brintellix, by gender? *:

female:

  1. Scoliosis (a medical condition in which a person's spine is curved from side to side)
  2. Sensation of foreign body
  3. Surgery
  4. Swollen tongue (swelling of tongue)
  5. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  6. Therapeutic response unexpected
  7. Tooth disorder (tooth disease)
  8. Weight decreased
  9. Weight increased
  10. Anxiety

male:

  1. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  2. Drug level decreased
  3. Cardiac disorder
  4. Diarrhoea
  5. Dizziness
  6. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  7. Gait disturbance
  8. Haemoglobin increased
  9. Headache (pain in head)
  10. Hypertension (high blood pressure)

What are the common drug interactions of Meloxicam and Brintellix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abscess (pus)
  2. Completed suicide (act of taking one's own life)
  3. Nausea (feeling of having an urge to vomit)
  4. Suicide attempt
  5. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  6. Hepatic enzyme increased
  7. Hepatic failure (liver failure)
  8. Laryngitis (inflammation of the larynx)
  9. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

30-39:

  1. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
  2. Memory impairment
  3. Myositis (inflammation of the muscles)
  4. Obsessive rumination (thinking and worry or rumination is an inability to gain control over recurrent, distressing thoughts, images)
  5. Papilloma viral infection
  6. Psychotic disorder
  7. Salivary hypersecretion (excess saliva secretion)
  8. Trismus (reduced opening of the jaws)
  9. Anxiety
  10. Deafness

40-49:

  1. Lethargy (tiredness)
  2. Unresponsive to stimuli
  3. Anxiety
  4. Arthralgia (joint pain)
  5. Back pain
  6. Cardiac disorder
  7. Chronic kidney disease
  8. Coma (state of unconsciousness lasting more than six hours)
  9. Dizziness
  10. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

50-59:

  1. Chronic kidney disease
  2. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Renal failure (kidney dysfunction)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Pruritus generalised (generalized itching)
  8. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

60+:

  1. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  2. Drug level decreased
  3. Nausea (feeling of having an urge to vomit)
  4. Renal failure (kidney dysfunction)
  5. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  6. Fall
  7. Upper limb fracture
  8. Bipolar disorder (mood disorder)
  9. Chronic kidney disease
  10. Dyspepsia (indigestion)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 32 people, 47.76%
  2. Stress And Anxiety: 23 people, 34.33%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 18 people, 26.87%
  4. Bipolar Disorder (mood disorder): 16 people, 23.88%
  5. Headache (pain in head): 15 people, 22.39%
  6. Back Pain: 14 people, 20.90%
  7. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 13 people, 19.40%
  8. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 13 people, 19.40%
  9. Memory Loss: 11 people, 16.42%
  10. Enlarged Prostate: 11 people, 16.42%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Meloxicam and Brintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Meloxicam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Brintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Meloxicam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Brintellix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on meloxicam and vortioxetine hydrobromide (the active ingredients of Meloxicam and Brintellix, respectively), and Meloxicam and Brintellix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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