Meloxicam and Cogentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Meloxicam (meloxicam) and Cogentin (benztropine mesylate). Common drug interactions include blood magnesium decreased among females and adverse event among males.

The phase IV clinical study analyzes what interactions people have when they take Meloxicam and Cogentin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Meloxicam?

Meloxicam has active ingredients of meloxicam. It is often used in arthritis. eHealthMe is studying from 68,017 Meloxicam users. Check the latest studies of Meloxicam.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

32 people who take Meloxicam and Cogentin together, and have interactions are studied.

Meloxicam and Cogentin drug interactions.

What are the common drug interactions of Meloxicam and Cogentin, by gender? *:

female:

Blood magnesium decreased
Blood prolactin increased
Body mass index increased
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral atrophy (decrement in size of brain)
Cerebral microangiopathy (small-vessel disease of brain)
Cerebral ventricle dilatation (enlargement of ventricle of brain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dizziness
Rash

male:

Adverse event
Arthralgia (joint pain)
Injection site erythema (redness at injection site)
Injection site swelling
Insomnia (sleeplessness)
Lumbar radiculopathy (radicular pain in the low back and legs)
Nail dystrophy (bed formation of nail)
Overdose
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Suicidal ideation

What are the common drug interactions of Meloxicam and Cogentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Adverse event
Blood prolactin increased
Galactorrhoea (secretion of breast milk in men)
Rash
Stomatitis (inflammation of mucous membrane of mouth)

30-39:

Blood glucose fluctuation
Cardiovascular disorder (heart diseases)
Deafness
Ear infection
Hypertension (high blood pressure)
Overdose
Weight increased

40-49:

Lymphadenopathy (disease or enlargement of lymph nodes)
Acute sinusitis
Blood pressure increased
Body mass index increased
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Ear pain
Facial paralysis (loss of function of face muscle)
Hypoaesthesia (reduced sense of touch or sensation)
Ingrowing nail
Injection site erosion

50-59:

Arthralgia (joint pain)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Constipation
Death
Dizziness
Erectile dysfunction
Lumbar radiculopathy (radicular pain in the low back and legs)
Malaise (a feeling of general discomfort or uneasiness)
Nail dystrophy (bed formation of nail)
Nightmare (unpleasant dream)

60+:

Activities of daily living impaired
Arthralgia (joint pain)
Enterococcus test positive
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastritis (inflammation of stomach)
Gastroenteritis (inflammation of stomach and intestine)
Gingival pain (gum pain)
Headache (pain in head)
Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 25.00%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 8 people, 25.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 21.88%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 18.75%
Constipation: 6 people, 18.75%
Scoliosis (a medical condition in which a person's spine is curved from side to side): 6 people, 18.75%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 18.75%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 5 people, 15.62%
Headache (pain in head): 4 people, 12.50%
High Blood Pressure: 4 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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