Meloxicam and Kombiglyze xr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Meloxicam (meloxicam) and Kombiglyze xr (metformin hydrochloride; saxagliptin). Common drug interactions include cardiac failure among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Meloxicam and Kombiglyze xr. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Meloxicam?

Meloxicam has active ingredients of meloxicam. It is often used in arthritis. eHealthMe is studying from 68,016 Meloxicam users. Check the latest studies of Meloxicam.

What is Kombiglyze xr?

Kombiglyze xr has active ingredients of metformin hydrochloride; saxagliptin. It is often used in diabetes. eHealthMe is studying from 2,680 Kombiglyze xr users. Check the latest studies of Kombiglyze xr.



On Jul, 11, 2026

44 people who take Meloxicam and Kombiglyze xr together, and have interactions are studied.

Meloxicam and Kombiglyze xr drug interactions.

What are the common drug interactions of Meloxicam and Kombiglyze Xr, by gender? *:

female:

  1. Cardiac failure
  2. Cardiac failure congestive
  3. Cardiovascular disorder (heart diseases)
  4. Acute myocardial infarction (acute heart attack)
  5. Chronic kidney disease
  6. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  7. Renal failure (kidney dysfunction)
  8. Acute left ventricular failure (heart attack)
  9. Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
  10. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)

male:

  1. Cardiac failure congestive
  2. Cardiovascular disorder (heart diseases)
  3. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  4. Nausea (feeling of having an urge to vomit)
  5. Abscess limb (limb infection)
  6. Acute myocardial infarction (acute heart attack)
  7. Anxiety
  8. Cellulitis (infection under the skin)
  9. Chronic kidney disease
  10. Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)

What are the common drug interactions of Meloxicam and Kombiglyze Xr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Cardiac failure congestive
  2. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  3. Cardiomegaly (increased size of heart than normal)
  4. Cardiovascular disorder (heart diseases)
  5. Dyspepsia (indigestion)
  6. Nausea (feeling of having an urge to vomit)
  7. Respiratory failure (inadequate gas exchange by the respiratory system)
  8. Abscess limb (limb infection)
  9. Anxiety
  10. Cellulitis (infection under the skin)

50-59:

  1. Cardiac failure
  2. Cardiac failure congestive
  3. Chronic kidney disease
  4. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  5. Acute left ventricular failure (heart attack)
  6. Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
  7. Arthralgia (joint pain)
  8. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
  9. Cardiovascular disorder (heart diseases)
  10. Death

60+:

  1. Cardiac failure
  2. Cardiac failure congestive
  3. Acute respiratory failure
  4. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  6. Weight fluctuation
  7. Cardiomyopathy (weakening of the heart muscle)
  8. Burning sensation
  9. Cough
  10. Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 14 people, 31.82%
  2. High Blood Cholesterol: 8 people, 18.18%
  3. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 11.36%
  4. Hypersensitivity: 5 people, 11.36%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 11.36%
  6. Stress And Anxiety: 4 people, 9.09%
  7. Pain: 4 people, 9.09%
  8. High Blood Pressure: 4 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Meloxicam and Kombiglyze xr?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Meloxicam and Kombiglyze xr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Meloxicam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Kombiglyze xr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Meloxicam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kombiglyze xr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on meloxicam and metformin hydrochloride; saxagliptin (the active ingredients of Meloxicam and Kombiglyze xr, respectively), and Meloxicam and Kombiglyze xr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: