Meloxicam and Otrexup drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Meloxicam (meloxicam) and Otrexup (methotrexate). Common drug interactions include pain in extremity among females and sinusitis among males.

The phase IV clinical study analyzes what interactions people have when they take Meloxicam and Otrexup. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Meloxicam?

Meloxicam has active ingredients of meloxicam. It is often used in arthritis. eHealthMe is studying from 68,017 Meloxicam users. Check the latest studies of Meloxicam.

What is Otrexup?

Otrexup has active ingredients of methotrexate. eHealthMe is studying from 2,154 Otrexup users. Check the latest studies of Otrexup.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

16 people who take Meloxicam and Otrexup together, and have interactions are studied.

Meloxicam and Otrexup drug interactions.

What are the common drug interactions of Meloxicam and Otrexup, by gender? *:

female:

Pain in extremity
Dry eye (lack of adequate tears)
Fibromyalgia (a long-term condition which causes pain all over the body)
Muscular weakness (muscle weakness)
Abdominal hernia
Allergy to chemicals
Back disorder
Bone density decreased
C-reactive protein increased
Crepitations (noises are produced by the rubbing of parts one against the other)

male:

Sinusitis (inflammation of sinus)

What are the common drug interactions of Meloxicam and Otrexup, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Dizziness
Fibromyalgia (a long-term condition which causes pain all over the body)
Nausea (feeling of having an urge to vomit)

50-59:

Gait disturbance
Muscular weakness (muscle weakness)
Nasal dryness (dry nose)
Pain in extremity
Renal disorder (kidney disease)
Decreased immune responsiveness
Drug ineffective
Arthralgia (joint pain)
Back disorder
Dry eye (lack of adequate tears)

60+:

Abdominal hernia
Procedural pain
Sinusitis (inflammation of sinus)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 68.75%
Pain: 3 people, 18.75%
Joint Pain: 2 people, 12.50%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 12.50%
Thyroid Diseases: 1 person, 6.25%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 6.25%
Neuropathy Peripheral (surface nerve damage): 1 person, 6.25%
Leukaemia (blood or bone marrow cancer): 1 person, 6.25%
High Blood Pressure: 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Meloxicam and Otrexup?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously