Melphalan hydrochloride and Cefazolin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melphalan hydrochloride (melphalan hydrochloride) and Cefazolin (cefazolin sodium). Common drug interactions include back pain among females and hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Melphalan hydrochloride and Cefazolin. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Melphalan hydrochloride?

Melphalan hydrochloride has active ingredients of melphalan hydrochloride. eHealthMe is studying from 3,970 Melphalan hydrochloride users. Check the latest studies of Melphalan hydrochloride.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.



On Jul, 06, 2026

22 people who take Melphalan hydrochloride and Cefazolin together, and have interactions are studied.

Melphalan hydrochloride and Cefazolin drug interactions.

What are the common drug interactions of Melphalan Hydrochloride and Cefazolin, by gender? *:

female:

  1. Back pain
  2. Blood glucose increased
  3. Bone density decreased
  4. Carcinoembryonic antigen increased
  5. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  6. Confusional state
  7. Decreased appetite
  8. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Dizziness

male:

  1. Hypertension (high blood pressure)
  2. Insomnia (sleeplessness)
  3. Arthralgia (joint pain)
  4. Asthenia (weakness)
  5. Blood magnesium decreased
  6. Blood sodium decreased
  7. Bone marrow disorder
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  10. Candidiasis (candidiasis or thrush is a fungal infection)

What are the common drug interactions of Melphalan Hydrochloride and Cefazolin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Cerebral haemorrhage (bleeding within the brain)
  2. Haemolytic anaemia (anaemia due to haemolysis)
  3. Idiopathic thrombocytopenic purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)
  4. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
  5. Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
  6. Enterococcal infection
  7. Enterococcal sepsis
  8. Neuroblastoma (a cancer that forms in your nerve tissue)

10-19:

n/a

20-29:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Hypertension (high blood pressure)
  3. Insomnia (sleeplessness)
  4. Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Post transplant lymphoproliferative disorder
  7. Pulmonary alveolar haemorrhage (acute bleeding)
  8. Renal failure (kidney dysfunction)
  9. Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
  10. Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

30-39:

  1. Neuropathy peripheral (surface nerve damage)

40-49:

  1. Cyst (a closed sac)
  2. Cytomegalovirus infection
  3. Decreased interest
  4. Dehydration (dryness resulting from the removal of water)
  5. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  8. Diarrhoea
  9. Dizziness
  10. Dry eye (lack of adequate tears)

50-59:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Back pain
  4. Blood glucose increased
  5. Bone density decreased
  6. Carcinoembryonic antigen increased
  7. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  8. Confusional state
  9. Decreased appetite
  10. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

60+:

  1. Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
  2. Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
  3. Calcium deficiency (lack of calcium)
  4. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  5. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  6. Cervical vertebral fracture
  7. Intervertebral disc degeneration (spinal disc degeneration)
  8. Intervertebral disc protrusion (spinal disc protrusion)
  9. Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
  10. Multiple fractures

What are the existing conditions these people have? *

  1. Bone Marrow Conditioning Regimen: 11 people, 50.00%
  2. Primary Immunodeficiency Syndrome: 4 people, 18.18%
  3. Plasmacytoma (neoplasm of plasma cells (usually in bone marrow)): 3 people, 13.64%
  4. High Blood Pressure: 3 people, 13.64%
  5. Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 9.09%
  6. Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Melphalan hydrochloride and Cefazolin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Melphalan hydrochloride and Cefazolin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Melphalan hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cefazolin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Melphalan hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefazolin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on melphalan hydrochloride and cefazolin sodium (the active ingredients of Melphalan hydrochloride and Cefazolin, respectively), and Melphalan hydrochloride and Cefazolin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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