Melphalan hydrochloride and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melphalan hydrochloride (melphalan hydrochloride) and Reglan (metoclopramide hydrochloride). Common drug interactions include anxiety among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Melphalan hydrochloride and Reglan. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Melphalan hydrochloride?

Melphalan hydrochloride has active ingredients of melphalan hydrochloride. eHealthMe is studying from 3,970 Melphalan hydrochloride users. Check the latest studies of Melphalan hydrochloride.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

59 people who take Melphalan hydrochloride and Reglan together, and have interactions are studied.

Melphalan hydrochloride and Reglan drug interactions.

What are the common drug interactions of Melphalan Hydrochloride and Reglan, by gender? *:

female:

Anxiety
Bone disorder
Cough
Diarrhoea
Hypercholesterolaemia (high levels of cholesterol in the blood)
Infection
Injury
Multiple myeloma (cancer of the plasma cells)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Aortic calcification (aortic calcification sign of heart valve disease)

male:

Anaemia (lack of blood)
Bone disorder
Neuropathy peripheral (surface nerve damage)
Pneumonia
Cellulitis (infection under the skin)
Dizziness
Gynaecomastia (enlargement of the gland tissue of the male breast)
Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
Multiple myeloma (cancer of the plasma cells)
Oedema (fluid collection in tissue)

What are the common drug interactions of Melphalan Hydrochloride and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain upper
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Dry skin
Injury
Insomnia (sleeplessness)
Mobility decreased (ability to move is reduced)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

40-49:

Anaemia (lack of blood)
Bone disorder
Dyspnoea (difficult or laboured respiration)
Neuropathy peripheral (surface nerve damage)
Osteonecrosis of jaw (death of bone of jaw)
Pneumonia
Intervertebral disc degeneration (spinal disc degeneration)
Pyrexia (fever)
Asthenia (weakness)
Dizziness

50-59:

Mobility decreased (ability to move is reduced)
Muscular weakness (muscle weakness)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Pain
Petechiae (a small red or purple spot caused by bleeding into the skin)
Pruritus (severe itching of the skin)
Rash papular (redness with papule)
Skin atrophy (wasting of skin)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Infection
Obesity (having too much body fat)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteoporosis (bones weak and more likely to break)
Asthenia (weakness)
Hypotension (abnormally low blood pressure)
Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 41 people, 69.49%
Nuclear Magnetic Resonance Imaging Brain: 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

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