Memantine and Paxlovid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Memantine (memantine) and Paxlovid (nirmatrelvir; ritonavir). Common drug interactions include diarrhoea among females and disease recurrence among males.

The phase IV clinical study analyzes what interactions people have when they take Memantine and Paxlovid. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 10,266 Memantine users. Check the latest studies of Memantine.

What is Paxlovid?

Paxlovid has active ingredients of nirmatrelvir; ritonavir. eHealthMe is studying from 38,421 Paxlovid users. Check the latest studies of Paxlovid.

On Jul, 26, 2026

15 people who take Memantine and Paxlovid together, and have interactions are studied.

Memantine and Paxlovid drug interactions.

What are the common drug interactions of Memantine and Paxlovid, by gender? *:

female:

Diarrhoea
Disease recurrence
Weight decreased
Anaemia (lack of blood)
Blood pressure decreased
Blood pressure systolic increased
C-reactive protein increased
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Constipation
Delirium (wild excitement)

male:

Disease recurrence
Confusional state
Death
Dysarthria (speech disorder)
Feeding disorder (when children refuse to eat certain food groups)
Lethargy (tiredness)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Vision blurred

What are the common drug interactions of Memantine and Paxlovid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Disease recurrence
Decreased appetite
Diarrhoea
Pancreatitis (inflammation of pancreas)
Vomiting
Weight decreased

50-59:

n/a

60+:

Cough
Disease recurrence
Death
Decreased appetite
Delirium (wild excitement)
Depressed level of consciousness
Diarrhoea
Dysarthria (speech disorder)
Dysgeusia (disorder of the sense of taste)
Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 13.33%
Dementia (madness): 2 people, 13.33%
Vascular Stenosis (abnormal narrowing blood vessels): 1 person, 6.67%
Stable Angina (a constant chest pain): 1 person, 6.67%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 6.67%
Memory Loss: 1 person, 6.67%
Iron Deficiency Anaemia: 1 person, 6.67%
Insomnia (sleeplessness): 1 person, 6.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.67%
Hypotension (abnormally low blood pressure): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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