Mephyton and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mephyton (phytonadione) and Azithromycin (azithromycin). Common drug interactions include renal failure chronic among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Mephyton and Azithromycin. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Mephyton?

Mephyton has active ingredients of phytonadione. eHealthMe is studying from 1,006 Mephyton users. Check the latest studies of Mephyton.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.



On Aug, 04, 2026

64 people who take Mephyton and Azithromycin together, and have interactions are studied.

Mephyton and Azithromycin drug interactions.

What are the common drug interactions of Mephyton and Azithromycin, by gender? *:

female:

  1. Renal failure chronic (long lasting kidney dysfunction)
  2. Impaired gastric emptying
  3. Knee arthroplasty
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Synovial cyst (cyst of joint filled with synovial fluid)
  6. Agitation (state of anxiety or nervous excitement)
  7. Contusion (a type of hematoma of tissue in which capillaries)
  8. Cystic fibrosis (disease of the secretary glands)
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Dehydration (dryness resulting from the removal of water)

male:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Visual field defect
  5. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  6. Heart rate increased
  7. Visual impairment
  8. Coagulopathy (blood's ability to clot is impaired)
  9. Injury
  10. Cystic fibrosis (disease of the secretary glands)

What are the common drug interactions of Mephyton and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Death

10-19:

  1. Abdominal pain upper
  2. Lung infection
  3. Nausea (feeling of having an urge to vomit)
  4. Pancreatitis (inflammation of pancreas)
  5. Weight decreased
  6. Cystic fibrosis (disease of the secretary glands)
  7. Alanine aminotransferase increased
  8. Aspartate aminotransferase increased
  9. Bacterial infection
  10. Bacterial test positive

20-29:

  1. Cough
  2. Intestinal obstruction
  3. Local swelling (swelling at the site of some application of substance or injury)
  4. Lower respiratory tract infection
  5. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  6. Staphylococcal infection (an infection with staphylococcus bacteria)
  7. Swelling face

30-39:

  1. Abortion spontaneous (naturally occurring miscarriage)
  2. Asthenia (weakness)
  3. Fatigue (feeling of tiredness)
  4. Pulmonary function test decreased
  5. Twin pregnancy (two babies in uterus)
  6. Blood pressure increased
  7. Chest pain
  8. Cystic fibrosis (disease of the secretary glands)
  9. Decreased appetite
  10. Heart rate increased

40-49:

  1. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  2. Abdominal discomfort
  3. Back pain
  4. Blood creatinine increased
  5. Blood urea increased
  6. Chest discomfort
  7. Chest pain
  8. Cough
  9. Decreased appetite
  10. Diarrhoea

50-59:

  1. Joint swelling
  2. Lung disorder (lung disease)
  3. Pain
  4. Peripheral swelling
  5. Weight increased
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Anxiety
  8. Arthralgia (joint pain)
  9. Crying
  10. Depression

60+:

  1. Anxiety
  2. Fatigue (feeling of tiredness)
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Osteomyelitis (infection of bone)
  5. Spinal column stenosis (narrowing of spinal column)
  6. Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
  7. Aphthous stomatitis (mouth ulcer)
  8. Back pain
  9. Depressed mood
  10. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 30 people, 46.88%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 10.94%
  3. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 5 people, 7.81%
  4. Cystic Fibrosis Lung (fibrosis with cyst in the lung): 4 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Mephyton and Azithromycin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mephyton and Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mephyton:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mephyton and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azithromycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on phytonadione and azithromycin (the active ingredients of Mephyton and Azithromycin, respectively), and Mephyton and Azithromycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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