Mephyton and Percocet drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Mephyton (phytonadione) and Percocet (acetaminophen; oxycodone hydrochloride). Common drug interactions include pleural effusion among females and vomiting among males.
The phase IV clinical study analyzes what interactions people have when they take Mephyton and Percocet. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Mephyton?
Mephyton has active ingredients of phytonadione. eHealthMe is studying from 1,006 Mephyton users. Check the latest studies of Mephyton.
What is Percocet?
Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.
25 people who take Mephyton and Percocet together, and have interactions are studied.

What are the common drug interactions of Mephyton and Percocet, by gender? *:
female:
- Pleural effusion (water on the lungs)
- Vomiting
- Arthralgia (joint pain)
- Benign neoplasm of thyroid gland (benign (non-cancerous) tumours of the thyroid gland)
- Bone disorder
- Colon neoplasm (cancer from uncontrolled cell growth in the colon or rectum)
- Decreased interest
- Defaecation urgency (a sudden compelling urge to defecate)
- Depression
- Dysfunctional uterine bleeding
male:
- Vomiting
- Dyspnoea (difficult or laboured respiration)
- Post procedural haemorrhage (post procedural bleeding)
- Skin ulcer
- Cardiac failure congestive
- Hypotension (abnormally low blood pressure)
- Lethargy (tiredness)
- Oedema peripheral (superficial swelling)
- Renal failure acute (rapid kidney dysfunction)
- Thrombocytopenia (decrease of platelets in blood)
What are the common drug interactions of Mephyton and Percocet, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Localised infection (infection at the single location)
- Nausea (feeling of having an urge to vomit)
- Vomiting
- Abscess (pus)
- Blood creatinine increased
- Exostosis (formation of new bone on the surface of a bone)
- International normalised ratio increased
- Muscular weakness (muscle weakness)
- Post procedural haemorrhage (post procedural bleeding)
- Skin ulcer
50-59:
- Chills (felling of cold)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Oedema peripheral (superficial swelling)
- Septic shock (shock due to blood infection)
- Staphylococcal bacteraemia (a bacterial infection of blood)
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)
- Abdominal pain
- Agitation (state of anxiety or nervous excitement)
- Anxiety
60+:
- Abdominal pain
- Anxiety
- Chest pain
- Diarrhoea
- Dizziness
- Endocarditis (inflammation in heart muscle)
- Fatigue (feeling of tiredness)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Lethargy (tiredness)
- Malaise (a feeling of general discomfort or uneasiness)
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 7 people, 28.00%
- High Blood Pressure: 6 people, 24.00%
- Nausea (feeling of having an urge to vomit): 5 people, 20.00%
- Itching: 5 people, 20.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 20.00%
- Constipation: 5 people, 20.00%
- Stress And Anxiety: 4 people, 16.00%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 16.00%
- Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 16.00%
- Diabetic Gastroparesis (paralysis of the muscles of the stomach caused by diabetes): 4 people, 16.00%
* Approximation only. Some reports may have incomplete information.
Do you take Mephyton and Percocet?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Mephyton and Percocet:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Mephyton:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Percocet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mephyton and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Percocet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on phytonadione and acetaminophen; oxycodone hydrochloride (the active ingredients of Mephyton and Percocet, respectively), and Mephyton and Percocet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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