Mepron and Combivir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mepron (atovaquone) and Combivir (lamivudine; zidovudine). Common drug interactions include osteoporosis among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Mepron and Combivir. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Mepron?

Mepron has active ingredients of atovaquone. It is often used in babesiosis. eHealthMe is studying from 2,091 Mepron users. Check the latest studies of Mepron.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.

On Jul, 27, 2026

56 people who take Mepron and Combivir together, and have interactions are studied.

What are the common drug interactions of Mepron and Combivir, by gender? *:

female:

Osteoporosis (bones weak and more likely to break)
Bone loss
Chronic kidney disease
Nausea (feeling of having an urge to vomit)
Osteonecrosis (death of bone)
Post-traumatic stress disorder
Rash
Deafness
Depression
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

Fatigue (feeling of tiredness)
Dyspnoea (difficult or laboured respiration)
Premature baby
Renal failure acute (rapid kidney dysfunction)
Blood bilirubin increased
Acute respiratory failure
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone marrow failure
C-reactive protein increased

What are the common drug interactions of Mepron and Combivir, by age (0-1 to 60+)? *:

0-1:

Cardiac murmur (an heart sound in valve abnormality)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Premature baby

2-9:

n/a

10-19:

n/a

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Rash
Chronic kidney disease
Depression
Nausea (feeling of having an urge to vomit)
Post-traumatic stress disorder
Decreased activity

30-39:

Pleural effusion (water on the lungs)
Pulmonary haemorrhage (acute bleeding from the lung)
Respiratory distress (difficulty in breathing)
Blood sodium decreased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Alanine aminotransferase increased
Anaemia (lack of blood)
Blood chloride decreased
Bone marrow disorder

40-49:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bone density decreased
Chronic kidney disease
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)
Acute respiratory failure
Bone loss
Bone marrow failure
C-reactive protein increased

50-59:

Anaemia (lack of blood)
Cardiac failure

60+:

Ileus (a painful obstruction of the ileum or other part of the intestine)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Small intestinal perforation (hole in small intestine)

What are the existing conditions these people have? *

Hiv Infection: 23 people, 41.07%
Fungal Infection: 3 people, 5.36%
Encephalitis Cytomegalovirus (inflammation of the brain due to cytomegalovirus): 3 people, 5.36%
Bacterial Infection: 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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