Mepron and Neulasta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Mepron (atovaquone) and Neulasta (pegfilgrastim). Common drug interactions include leukocytosis among females and febrile neutropenia among males.
The phase IV clinical study analyzes what interactions people have when they take Mepron and Neulasta. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Mepron?
Mepron has active ingredients of atovaquone. It is often used in babesiosis. eHealthMe is studying from 2,091 Mepron users. Check the latest studies of Mepron.
What is Neulasta?
Neulasta has active ingredients of pegfilgrastim. It is often used in agranulocytosis. eHealthMe is studying from 92,286 Neulasta users. Check the latest studies of Neulasta.
20 people who take Mepron and Neulasta together, and have interactions are studied.

What are the common drug interactions of Mepron and Neulasta, by gender? *:
female:
- Leukocytosis (increased white blood cells)
- Anaemia (lack of blood)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Diarrhoea
- Diplopia (double vision)
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Febrile neutropenia (fever with reduced white blood cells)
- Hypokalaemia (low potassium)
- Melaena (the passage of black, tarry stools)
- Myasthenic syndrome (a group of conditions characterized by muscle weakness (myasthenia) that worsens with physical exertion)
male:
- Febrile neutropenia (fever with reduced white blood cells)
- Bacteraemia (presence of bacteria in the blood)
- Escherichia urinary tract infection (urinary tract infection by escherichia coli)
- Prostatic abscess (a closed pocket containing pus within the prostate)
- Urethral fistula
- Lymphocyte count decreased
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Platelet count decreased
- White blood cell count decreased
- Lung infection
What are the common drug interactions of Mepron and Neulasta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Multiple myeloma (cancer of the plasma cells)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Death
50-59:
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Leukocytosis (increased white blood cells)
60+:
- Febrile neutropenia (fever with reduced white blood cells)
- Bacteraemia (presence of bacteria in the blood)
- Diplopia (double vision)
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Hypokalaemia (low potassium)
- Leukocytosis (increased white blood cells)
- Melaena (the passage of black, tarry stools)
- Myasthenic syndrome (a group of conditions characterized by muscle weakness (myasthenia) that worsens with physical exertion)
- Procedural pain
- Thrombocytopenia (decrease of platelets in blood)
What are the existing conditions these people have? *
- Stress And Anxiety: 13 people, 65.00%
- Nausea (feeling of having an urge to vomit): 9 people, 45.00%
- Nausea And Vomiting: 8 people, 40.00%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 8 people, 40.00%
- Constipation: 7 people, 35.00%
- Diarrhea: 5 people, 25.00%
- Akathisia (a movement disorder characterized by a feeling of inner restlessness): 5 people, 25.00%
- Flatulence (flatus expelled through the anus): 5 people, 25.00%
- High Blood Pressure: 4 people, 20.00%
- Hypokalemia (low potassium): 4 people, 20.00%
* Approximation only. Some reports may have incomplete information.
Do you take Mepron and Neulasta?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Mepron and Neulasta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Mepron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Neulasta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mepron and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Neulasta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Khan A, Yasin Z, "Hyperleukocytosis Caused By Neulasta Complicated By Leukostasis Versus Asymptomatic Uncomplicated Hyperleukocytosis In AML. Two Cases and When To Leukapherese.", Am Soc Hematology, 2017 Jan .
- Khan A, Yasin Z, "Hyperleukocytosis Caused By Neulasta Complicated By Leukostasis Versus Asymptomatic Uncomplicated Hyperleukocytosis In AML. Two Cases and When To Leukapherese.", Am Soc Hematology, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on atovaquone and pegfilgrastim (the active ingredients of Mepron and Neulasta, respectively), and Mepron and Neulasta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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