Meropenem and Lacosamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Meropenem (meropenem) and Lacosamide (lacosamide). Common drug interactions include cardio-respiratory arrest among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Meropenem and Lacosamide. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Meropenem?

Meropenem has active ingredients of meropenem. eHealthMe is studying from 33,295 Meropenem users. Check the latest studies of Meropenem.

What is Lacosamide?

Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.

On Jul, 30, 2026

83 people who take Meropenem and Lacosamide together, and have interactions are studied.

Meropenem and Lacosamide drug interactions.

What are the common drug interactions of Meropenem and Lacosamide, by gender? *:

female:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Depressed level of consciousness
Enterococcal infection
Erythema multiforme (a type of hypersensitivity reaction)
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
Generalised oedema (swelling all over the body)
Leukopenia (less number of white blood cells in blood)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Restlessness (not able to rest)
Septic shock (shock due to blood infection)

male:

Drug ineffective
Neutropenia (an abnormally low number of neutrophils)
Constipation
Erythema migrans (lyme disease develop a red rash)
Fatigue (feeling of tiredness)
Hyperammonaemia
Malignant neoplasm progression (cancer tumour came back)
Peripheral motor neuropathy (muscles in the body become progressively weaker over months to years)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Telangiectasia (small dilated blood vessels near the surface of the skin)

What are the common drug interactions of Meropenem and Lacosamide, by age (0-1 to 60+)? *:

0-1:

Bacterial sepsis
Brain death
Hypotension (abnormally low blood pressure)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Drug ineffective

2-9:

Drug ineffective
Neutropenia (an abnormally low number of neutrophils)
Hyperammonaemia
Abdominal distension
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Heart rate increased
Hypotension (abnormally low blood pressure)
Labile blood pressure (wildly fluctuating blood pressure)
Pleural effusion (water on the lungs)
Pyrexia (fever)

10-19:

Cardiac arrest
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Coagulopathy (blood's ability to clot is impaired)
Death
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Haemoglobin decreased
Haemorrhage (bleeding)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Neuropathy peripheral (surface nerve damage)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

20-29:

Drug ineffective
Drug level decreased
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Pyrexia (fever)
Drug level below therapeutic
Hyperammonaemia
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sepsis (a severe blood infection that can lead to organ failure and death)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)

30-39:

Pericardial effusion (fluid around the heart)
Toxic skin eruption (skin breakdown due to toxic substance)
Infection reactivation

40-49:

Cutaneous vasculitis (an inflammatory process affecting the vessel wall that leads to its damage)
Encephalitis (inflammation of the brain)
Erythema multiforme (a type of hypersensitivity reaction)
Abdominal pain upper
Alanine aminotransferase increased
Aspartate aminotransferase increased
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Pleural effusion (water on the lungs)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Sensitisation (the state of being sensitive)

50-59:

Drug ineffective
Abdominal sepsis (abdominal infection)
Pneumonia
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Hyperammonaemia
Punctate keratitis (inflammation of the cornea with tiny spots)
Sepsis (a severe blood infection that can lead to organ failure and death)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Ureaplasma infection
Agitation (state of anxiety or nervous excitement)

60+:

Autoimmune pancreatitis (autoimmune pancreatitis (aip) is an increasingly recognized type of chronic pancreatitis)
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Rash
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Telangiectasia (small dilated blood vessels near the surface of the skin)
Transaminases increased
Vertigo
Xerosis (abnormal dryness of the skin or mucus membranes)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Diarrhoea

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 19 people, 22.89%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 16 people, 19.28%
Sepsis (a severe blood infection that can lead to organ failure and death): 12 people, 14.46%
Pneumonia: 11 people, 13.25%
Partial Seizures (seizures which affect only a part of the brain at onset): 10 people, 12.05%
Insomnia (sleeplessness): 8 people, 9.64%
Diarrhea: 8 people, 9.64%
Malignant Melanoma (skin cancer rises from melancytes): 6 people, 7.23%
Conjunctivitis (pink eye): 6 people, 7.23%
Ulcerative Keratitis (ulcerative inflammation of the cornea): 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

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