Mesalamine and Aventyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mesalamine (mesalamine) and Aventyl (nortriptyline hydrochloride). Common drug interactions include general physical health deterioration among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Mesalamine and Aventyl. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

What is Aventyl?

Aventyl has active ingredients of nortriptyline hydrochloride. eHealthMe is studying from 515 Aventyl users. Check the latest studies of Aventyl.

On Jul, 07, 2026

16 people who take Mesalamine and Aventyl together, and have interactions are studied.

Mesalamine and Aventyl drug interactions.

What are the common drug interactions of Mesalamine and Aventyl, by gender? *:

female:

General physical health deterioration (weak health status)
Coeliac disease (simple food intolerance)
Infection
Injection site erythema (redness at injection site)
Injection site pain
Injection site warmth
Swelling face
Abdominal pain
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Blood pressure increased

male:

Death

What are the common drug interactions of Mesalamine and Aventyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Blood pressure increased
Burning sensation
Dehydration (dryness resulting from the removal of water)
Discomfort
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Heart rate increased
Hypoaesthesia (reduced sense of touch or sensation)

40-49:

Abdominal pain lower
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Poor venous access
Swelling face

50-59:

Drug effect decreased
Frequent bowel movements
General physical health deterioration (weak health status)
Haematochezia (passage of stools containing blood)

60+:

Abdominal distension
Coeliac disease (simple food intolerance)
Haematochezia (passage of stools containing blood)
Liver disorder (liver diseases)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pyrexia (fever)
Rash macular (small, flat red spots)
Infection
Injection site erythema (redness at injection site)
Injection site pain

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 43.75%
Asthma: 5 people, 31.25%
Immunodeficiency Common Variable: 2 people, 12.50%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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