Mesalamine and Cephalexin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Mesalamine (mesalamine) and Cephalexin (cephalexin). Common drug interactions include renal injury among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Mesalamine and Cephalexin. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.
What is Mesalamine?
Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.
What is Cephalexin?
Cephalexin has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 30,580 Cephalexin users. Check the latest studies of Cephalexin.
71 people who take Mesalamine and Cephalexin together, and have interactions are studied.

What are the common drug interactions of Mesalamine and Cephalexin, by gender? *:
female:
- Renal injury (kidney injury)
- Anaemia (lack of blood)
- Weight decreased
- Abscess bacterial (collection of pus caused by bacteria)
- Angioedema (rapid swelling of the dermis)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bacteraemia (presence of bacteria in the blood)
- Bacterial infection
- Depressed mood
male:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Hip fracture
- Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
- Multiple fractures
- Osteoporosis (bones weak and more likely to break)
- Wrist fracture
- Abnormal dreams
- Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
What are the common drug interactions of Mesalamine and Cephalexin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Abscess bacterial (collection of pus caused by bacteria)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Clostridial infection (infectious conditions by clostridium bacteria)
- Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
- Gallbladder injury
- Hepatosplenic t-cell lymphoma (neoplasm comprising medium-sized cytotoxic t-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow)
- Pain
- Pancreatitis (inflammation of pancreas)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Psoriasis (immune-mediated disease that affects the skin)
20-29:
n/a
30-39:
- Rash
- Swelling face
- Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
- Hypersensitivity
- Idiosyncratic drug reaction (unusual effect of the medication)
- Hepatitis infectious mononucleosis (inflammation of the liver caused by epstein-barr virus)
- Abdominal pain
- Abdominal distension
- Abdominal pain upper
- Abnormal sensation in eye
40-49:
- Chronic kidney disease
- Osteoporosis (bones weak and more likely to break)
- Renal failure (kidney dysfunction)
- Angioedema (rapid swelling of the dermis)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Bacterial infection
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Drug ineffective
- Drug intolerance (drug sensitivity)
50-59:
- Wrist fracture
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bipolar disorder (mood disorder)
- Depression
- Emotional distress
- Fracture
- Hip fracture
60+:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Pain
- Cough
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Abdominal pain
- Abdominal wall mass
What are the existing conditions these people have? *
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 17 people, 23.94%
- Pain: 15 people, 21.13%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 14.08%
- High Blood Pressure: 9 people, 12.68%
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 8 people, 11.27%
- Choledocholithiasis (stones in the common bile duct): 8 people, 11.27%
- Inflammatory Bowel Disease: 6 people, 8.45%
- Hiv Infection: 6 people, 8.45%
- Migraine (headache): 5 people, 7.04%
- High Blood Cholesterol: 5 people, 7.04%
* Approximation only. Some reports may have incomplete information.
Do you take Mesalamine and Cephalexin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Mesalamine (28,053 reports)
- Cephalexin (30,580 reports)
Browse all drug interactions of Mesalamine and Cephalexin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Mesalamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cephalexin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mesalamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cephalexin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on mesalamine and cephalexin (the active ingredients of Mesalamine and Cephalexin, respectively), and Mesalamine and Cephalexin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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