Mesalamine and Hyrimoz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mesalamine (mesalamine) and Hyrimoz (adalimumab-adaz). Common drug interactions include malaise among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Mesalamine and Hyrimoz. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

What is Hyrimoz?

Hyrimoz has active ingredients of adalimumab-adaz. eHealthMe is studying from 4,635 Hyrimoz users. Check the latest studies of Hyrimoz.



On Jul, 08, 2026

37 people who take Mesalamine and Hyrimoz together, and have interactions are studied.

Mesalamine and Hyrimoz drug interactions.

What are the common drug interactions of Mesalamine and Hyrimoz, by gender? *:

female:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Abdominal pain
  3. Drug ineffective
  4. Diarrhoea haemorrhagic (bloody diarrhoea)
  5. Therapeutic response decreased (less preventive response)
  6. Constipation
  7. Haematochezia (passage of stools containing blood)
  8. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  9. Rectal haemorrhage (bleeding from anus)
  10. Erythema (redness of the skin)

male:

  1. Asthenia (weakness)
  2. Cough
  3. Anxiety
  4. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  5. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  6. Secretion discharge
  7. Arthralgia (joint pain)
  8. Intestinal adenocarcinoma (intestinal cancer)
  9. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  10. Pain in extremity

What are the common drug interactions of Mesalamine and Hyrimoz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Asthenia (weakness)
  2. Cough
  3. Dyspnoea (difficult or laboured respiration)
  4. Fatigue (feeling of tiredness)
  5. Headache (pain in head)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Pyrexia (fever)
  10. Sinusitis (inflammation of sinus)

30-39:

  1. Abdominal discomfort
  2. Abdominal distension
  3. Abdominal pain
  4. Arthralgia (joint pain)
  5. Bowel movement irregularity
  6. Diarrhoea
  7. Dyspepsia (indigestion)
  8. Fatigue (feeling of tiredness)
  9. Lactose intolerance (inability to digest lactose)
  10. Pyrexia (fever)

40-49:

  1. Anxiety
  2. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  3. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  4. Secretion discharge

50-59:

  1. Ankylosing spondylitis (type of arthritis affecting the spine)
  2. Breast cancer
  3. Injection site erythema (redness at injection site)
  4. Injection site pain
  5. Injection site pruritus (severe itching at injection site)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Oropharyngeal pain
  8. Pain
  9. Pneumonia
  10. Arthralgia (joint pain)

60+:

  1. Abdominal pain
  2. Drug ineffective
  3. Dyspepsia (indigestion)
  4. Erythema (redness of the skin)
  5. Female genital tract fistula (passage in genital tract of female)
  6. Frequent bowel movements
  7. Headache (pain in head)
  8. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  9. Nausea (feeling of having an urge to vomit)
  10. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 20 people, 54.05%
  2. Ankylosing Spondylitis (type of arthritis affecting the spine): 7 people, 18.92%
  3. Allergies: 4 people, 10.81%

* Approximation only. Some reports may have incomplete information.

Do you take Mesalamine and Hyrimoz?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mesalamine and Hyrimoz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mesalamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hyrimoz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mesalamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hyrimoz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mesalamine and adalimumab-adaz (the active ingredients of Mesalamine and Hyrimoz, respectively), and Mesalamine and Hyrimoz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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