Mesalamine and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mesalamine (mesalamine) and Keppra (levetiracetam). Common drug interactions include weight decreased among females and upper gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Mesalamine and Keppra. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

On Aug, 03, 2026

30 people who take Mesalamine and Keppra together, and have interactions are studied.

Mesalamine and Keppra drug interactions.

What are the common drug interactions of Mesalamine and Keppra, by gender? *:

female:

Weight decreased
Influenza
Sedation
Pain
Weight increased
Haemoglobin decreased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Drug ineffective
Emotional distress

male:

Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Amyloidosis (a tumour within which amyloid is produced)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Malignant neoplasm progression (cancer tumour came back)
Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
Rash
Asthenia (weakness)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diabetes mellitus inadequate control

What are the common drug interactions of Mesalamine and Keppra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Activated partial thromboplastin time prolonged
Blood fibrinogen increased
Blood triglycerides increased
Coagulation time prolonged
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Gastroenteritis (inflammation of stomach and intestine)
Haemoglobin decreased
Haemorrhage (bleeding)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
General physical health deterioration (weak health status)
Injury
Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
Pain
Transverse sinus thrombosis (a blood clot in transverse sinus)

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aphasia (damage to the parts of the brain that control language)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Depression
Disturbance in attention
Dizziness
Emotional distress
General physical health deterioration (weak health status)

40-49:

Chronic kidney disease
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diabetes mellitus inadequate control
Haemorrhage (bleeding)
Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
Rash
Renal failure (kidney dysfunction)

50-59:

Abscess (pus)
Asthenia (weakness)
Fatigue (feeling of tiredness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Thymus enlargement

60+:

Influenza
Sedation
Herpes zoster
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Lung neoplasm malignant (cancer tumour of lung)
Suicidal ideation
Weight fluctuation
Weight decreased
Weight increased
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

What are the existing conditions these people have? *

Sleep Apnea Syndrome: 5 people, 16.67%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 16.67%
Primary Myelofibrosis (primary disorder of the bone marrow): 4 people, 13.33%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 13.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 13.33%
Drowsiness: 4 people, 13.33%
Renal Cell Carcinoma (a kidney cancer): 3 people, 10.00%
Pain: 3 people, 10.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 10.00%
Migraine (headache): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Mesalamine and Keppra?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously