Mesalamine and Lactobacillus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mesalamine (mesalamine) and Lactobacillus (lactobacillus). Common drug interactions include alopecia among females and intestinal obstruction among males.

The phase IV clinical study analyzes what interactions people have when they take Mesalamine and Lactobacillus. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

What is Lactobacillus?

Lactobacillus has active ingredients of lactobacillus. It is often used in stomach discomfort. eHealthMe is studying from 5,854 Lactobacillus users. Check the latest studies of Lactobacillus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

81 people who take Mesalamine and Lactobacillus together, and have interactions are studied.

Mesalamine and Lactobacillus drug interactions.

What are the common drug interactions of Mesalamine and Lactobacillus, by gender? *:

female:

  1. Alopecia (absence of hair from areas of the body)
  2. Bacteraemia (presence of bacteria in the blood)
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Diarrhoea haemorrhagic (bloody diarrhoea)
  5. Haemoglobin increased
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Oedema (fluid collection in tissue)
  8. Oropharyngeal pain
  9. Paresis (a condition of muscular weakness)
  10. Pneumonia

male:

  1. Intestinal obstruction
  2. Osteopenia (a condition where bone mineral density is lower than normal)
  3. Nasopharyngitis (inflammation of the nasopharynx)
  4. Salmonellosis (an infection with salmonella bacteria)
  5. Abdominal pain
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Anxiety
  8. Blood calcium decreased
  9. Decreased activity
  10. Drug ineffective

What are the common drug interactions of Mesalamine and Lactobacillus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal pain
  2. Rectal abscess (pus in rectum)
  3. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
  4. Proctitis (inflammation of the rectum and anus)
  5. Back pain
  6. Decreased appetite
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Infusion related reaction
  9. Muscular weakness (muscle weakness)
  10. Overdose

20-29:

  1. Intestinal obstruction
  2. Diarrhoea haemorrhagic (bloody diarrhoea)

30-39:

  1. Pancreatitis acute (sudden inflammation of pancreas)
  2. Pyrexia (fever)
  3. Subileus
  4. Vomiting
  5. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  6. Alopecia (absence of hair from areas of the body)
  7. Anal abscess
  8. Angioedema (rapid swelling of the dermis)
  9. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  10. Asthenia (weakness)

40-49:

  1. Blood culture positive
  2. Blood glucose increased
  3. Blood triglycerides increased
  4. Chest pain
  5. Diarrhoea haemorrhagic (bloody diarrhoea)
  6. Drug effect decreased
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Hypokinesia (decreased bodily movement)
  9. Joint stiffness
  10. Lacrimation increased

50-59:

  1. Diarrhoea
  2. Vascular occlusion (sudden blockage of a blood vessel, usually with a clot)
  3. Neoplasm malignant (cancer tumour)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Osteopenia (a condition where bone mineral density is lower than normal)
  6. Pain
  7. Cerebral haemorrhage (bleeding within the brain)
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Emotional distress
  10. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

60+:

  1. Fatigue (feeling of tiredness)
  2. Anaemia (lack of blood)
  3. Vomiting
  4. Abdominal pain upper
  5. Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
  6. Blood erythropoietin increased
  7. Decreased appetite
  8. Drug hypersensitivity
  9. Haptoglobin increased
  10. Iron deficiency anaemia

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 22 people, 27.16%
  2. Inflammatory Bowel Disease: 20 people, 24.69%
  3. Diarrhea: 10 people, 12.35%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 11.11%
  5. Peripheral Arterial Occlusive Disease (reproducible ischemic muscle pain): 7 people, 8.64%
  6. Malignant Melanoma (skin cancer rises from melancytes): 7 people, 8.64%
  7. High Blood Pressure: 7 people, 8.64%
  8. Pain: 5 people, 6.17%
  9. Irritable Bowel Syndrome: 5 people, 6.17%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 6.17%

* Approximation only. Some reports may have incomplete information.

Do you take Mesalamine and Lactobacillus?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mesalamine and Lactobacillus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mesalamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lactobacillus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mesalamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lactobacillus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mesalamine and lactobacillus (the active ingredients of Mesalamine and Lactobacillus, respectively), and Mesalamine and Lactobacillus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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