Mesalamine and Memantine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mesalamine (mesalamine) and Memantine (memantine). Common drug interactions include autism spectrum disorder among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Mesalamine and Memantine. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 10,266 Memantine users. Check the latest studies of Memantine.



On Jul, 15, 2026

34 people who take Mesalamine and Memantine together, and have interactions are studied.

Mesalamine and Memantine drug interactions.

What are the common drug interactions of Mesalamine and Memantine, by gender? *:

female:

  1. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  2. Diarrhoea
  3. Ear infection
  4. Fungal infection
  5. Gastric infection (infection of stomach)
  6. Gastrointestinal viral infection (virus infection of gastrointestinal tract)
  7. Haemorrhage (bleeding)
  8. Influenza
  9. Mouth ulceration (mouth ulcers)
  10. Polyp

male:

  1. Abdominal pain upper
  2. Blood potassium decreased
  3. Nephrolithiasis (calculi in the kidneys)
  4. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  5. Repetitive speech
  6. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  7. Terminal state (the transitional states between life and biological death)
  8. Urinary tract disorder
  9. Weight decreased
  10. White blood cell count increased

What are the common drug interactions of Mesalamine and Memantine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Confusional state
  2. Death
  3. Injection site pain
  4. Nephrolithiasis (calculi in the kidneys)
  5. Repetitive speech
  6. Respiratory failure (inadequate gas exchange by the respiratory system)
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Terminal state (the transitional states between life and biological death)
  9. Urinary tract disorder
  10. Weight decreased

What are the existing conditions these people have? *

  1. Parkinson's Disease: 5 people, 14.71%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 11.76%
  3. Delusion (a false belief or opinion): 4 people, 11.76%
  4. Memory Loss: 4 people, 11.76%
  5. Hallucinations (sensations that appear real but are created by your mind): 4 people, 11.76%
  6. Muscle Spasms (muscle contraction): 3 people, 8.82%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 8.82%
  8. Immunodeficiency Common Variable: 3 people, 8.82%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.82%
  10. Respiratory Tract Congestion (blockage on respiratory system): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mesalamine and Memantine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mesalamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Memantine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mesalamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Memantine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mesalamine and memantine (the active ingredients of Mesalamine and Memantine, respectively), and Mesalamine and Memantine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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