Mesalamine and Naltrexone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mesalamine (mesalamine) and Naltrexone (naltrexone). Common drug interactions include abdominal pain among females and bile duct stenosis among males.

The phase IV clinical study analyzes what interactions people have when they take Mesalamine and Naltrexone. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

What is Naltrexone?

Naltrexone has active ingredients of naltrexone. eHealthMe is studying from 4,835 Naltrexone users. Check the latest studies of Naltrexone.

On Jul, 31, 2026

14 people who take Mesalamine and Naltrexone together, and have interactions are studied.

Mesalamine and Naltrexone drug interactions.

What are the common drug interactions of Mesalamine and Naltrexone, by gender? *:

female:

Abdominal pain
Arthralgia (joint pain)
Foetal death (death of foetus)
Haematochezia (passage of stools containing blood)
Pregnancy
Abdominal discomfort
Blepharospasm (any abnormal contraction or twitch of the eyelid)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cellulitis (infection under the skin)
Dehydration (dryness resulting from the removal of water)

male:

Bile duct stenosis (abnormal narrowing of the common bile duct)
Biliary dilatation
Nasopharyngitis (inflammation of the nasopharynx)
Pain
Pyrexia (fever)
Viral infection
Pneumonia
Bowel movement irregularity
Cholangitis sclerosing (infection and obstruction of bile duct)
Drug hypersensitivity

What are the common drug interactions of Mesalamine and Naltrexone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Foetal death (death of foetus)
Pregnancy
Frequent bowel movements
Abdominal pain
Bile duct stenosis (abnormal narrowing of the common bile duct)
Biliary dilatation
Bowel movement irregularity
Cholangitis sclerosing (infection and obstruction of bile duct)
Drug hypersensitivity
Drug ineffective

40-49:

Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Blood pressure fluctuation
Contusion (a type of hematoma of tissue in which capillaries)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Insomnia (sleeplessness)
Joint swelling
Pain
Pain of skin
Skin discolouration (change of skin colour)

50-59:

Abdominal discomfort
Abdominal pain
Haematochezia (passage of stools containing blood)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Malignant neoplasm progression (cancer tumour came back)
Metastases to bone (cancer spreads to bone)
Metastases to liver (cancer spreads to liver)
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Pancreatic carcinoma (pancreatic cancer)

60+:

n/a

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 42.86%
Pain: 4 people, 28.57%
Stress And Anxiety: 3 people, 21.43%
Hormone Level Abnormal: 3 people, 21.43%
Constipation: 3 people, 21.43%
Cough: 3 people, 21.43%
Cystitis Interstitial (unknown cause characterized by bladder pain): 3 people, 21.43%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 21.43%
Fungal Infection: 3 people, 21.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

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