Mestinon and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mestinon (pyridostigmine bromide) and Azithromycin (azithromycin). Common drug interactions include pain among females.

The phase IV clinical study analyzes what interactions people have when they take Mestinon and Azithromycin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Mestinon?

Mestinon has active ingredients of pyridostigmine bromide. It is often used in myasthenia gravis. eHealthMe is studying from 5,948 Mestinon users. Check the latest studies of Mestinon.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 25, 2026

20 people who take Mestinon and Azithromycin together, and have interactions are studied.

Mestinon and Azithromycin drug interactions.

What are the common drug interactions of Mestinon and Azithromycin, by gender? *:

female:

  1. Pain
  2. Alopecia (absence of hair from areas of the body)
  3. Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
  4. Urinary tract infection
  5. Anaphylactic reaction (serious allergic reaction)
  6. Breast cancer metastatic
  7. Chest discomfort
  8. Chronic kidney disease
  9. Disease progression
  10. Dysphagia (a condition in which swallowing is difficult or painful)

male:

n/a

What are the common drug interactions of Mestinon and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fungal infection
  3. Hypersensitivity
  4. Respiratory tract infection

40-49:

  1. Chronic kidney disease
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Dyspnoea (difficult or laboured respiration)
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Respiratory disorder (respiratory disease)
  6. Speech disorder

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Drug ineffective
  3. Fatigue (feeling of tiredness)
  4. Headache (pain in head)
  5. Urinary tract infection
  6. Chest discomfort
  7. Disease progression
  8. Dyspnoea (difficult or laboured respiration)
  9. Fall
  10. Foot fracture

60+:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Laryngeal oedema (swelling of larynx)
  3. Liver disorder (liver diseases)
  4. Lung disorder (lung disease)
  5. Myasthenia gravis crisis (a paralysis of the respiratory muscles occurs)
  6. Pancreatic disorder
  7. Respiratory syncytial virus infection (viral disease of respiratory system)
  8. Small cell lung cancer (small cell cancer tumour of lung)
  9. Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)

What are the existing conditions these people have? *

  1. High Blood Pressure: 3 people, 15.00%
  2. Urinary Tract Infection: 2 people, 10.00%
  3. Insomnia (sleeplessness): 2 people, 10.00%
  4. Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 10.00%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 10.00%
  6. Upper Respiratory Tract Infection: 2 people, 10.00%
  7. Immunodeficiency: 2 people, 10.00%
  8. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 10.00%
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 10.00%
  10. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Mestinon and Azithromycin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mestinon and Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mestinon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mestinon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azithromycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pyridostigmine bromide and azithromycin (the active ingredients of Mestinon and Azithromycin, respectively), and Mestinon and Azithromycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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