Mestinon and Dulcolax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mestinon (pyridostigmine bromide) and Dulcolax (bisacodyl). Common drug interactions include embolism venous among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Mestinon and Dulcolax. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Mestinon?

Mestinon has active ingredients of pyridostigmine bromide. It is often used in myasthenia gravis. eHealthMe is studying from 5,948 Mestinon users. Check the latest studies of Mestinon.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.



On Jul, 11, 2026

21 people who take Mestinon and Dulcolax together, and have interactions are studied.

Mestinon and Dulcolax drug interactions.

What are the common drug interactions of Mestinon and Dulcolax, by gender? *:

female:

  1. Embolism venous (embolus may pass into the arterial system)
  2. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  3. Influenza
  4. Light chain analysis increased
  5. Limb discomfort (discomfort in leg)
  6. Muscle spasms (muscle contraction)
  7. Myalgia (muscle pain)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  10. Pulmonary mass

male:

  1. Asthenia (weakness)
  2. Balance disorder
  3. Anticoagulation drug level above therapeutic
  4. Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
  5. Atelectasis (partial or complete collapse of the lung)
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Back injury
  8. Back pain
  9. Blood pressure decreased
  10. Bradycardia (abnormally slow heart action)

What are the common drug interactions of Mestinon and Dulcolax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Asthenia (weakness)
  2. Balance disorder
  3. Injury
  4. Limb discomfort (discomfort in leg)
  5. Loss of consciousness
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Muscle spasms (muscle contraction)
  8. Myalgia (muscle pain)
  9. Fall
  10. Abdominal pain upper

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 33.33%
  2. Parkinson's Disease: 6 people, 28.57%
  3. Hallucinations (sensations that appear real but are created by your mind): 4 people, 19.05%
  4. Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 14.29%
  5. Multiple Myeloma (cancer of the plasma cells): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Mestinon and Dulcolax?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mestinon and Dulcolax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mestinon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dulcolax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mestinon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dulcolax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pyridostigmine bromide and bisacodyl (the active ingredients of Mestinon and Dulcolax, respectively), and Mestinon and Dulcolax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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