Mestinon and Hydrocortisone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mestinon (pyridostigmine bromide) and Hydrocortisone (hydrocortisone). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Mestinon and Hydrocortisone. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Mestinon?

Mestinon has active ingredients of pyridostigmine bromide. It is often used in myasthenia gravis. eHealthMe is studying from 5,948 Mestinon users. Check the latest studies of Mestinon.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

On Jul, 05, 2026

39 people who take Mestinon and Hydrocortisone together, and have interactions are studied.

Mestinon and Hydrocortisone drug interactions.

What are the common drug interactions of Mestinon and Hydrocortisone, by gender? *:

female:

Fatigue (feeling of tiredness)
Sinusitis (inflammation of sinus)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Conjunctivitis (pink eye)
Diarrhoea
Nail infection
Nausea (feeling of having an urge to vomit)
Vomiting
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Infusion site bruising

male:

n/a

What are the common drug interactions of Mestinon and Hydrocortisone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Poor peripheral circulation
Pulmonary embolism (blockage of the main artery of the lung)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Urinary tract infection
Vomiting
Weight increased

40-49:

Blood glucose increased
Blood pressure increased
Chills (felling of cold)
Concussion (short loss of normal brain function in response to a head injury)
Escherichia test positive
Fall
Haematoma (collection of blood outside the blood vessels)
Hypotension (abnormally low blood pressure)
Infusion related reaction
Upper respiratory tract infection

50-59:

Jaundice cholestatic
Oedema peripheral (superficial swelling)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Dehydration (dryness resulting from the removal of water)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Fatigue (feeling of tiredness)
Headache (pain in head)
Hordeolum (small collection of pus (abscess) on the eyelid)
Joint stiffness
Post procedural infection

60+:

Diarrhoea
Lung disorder (lung disease)
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Femur fracture
Hereditary angioedema (recurrent episodes of severe swelling)
Hypersensitivity
Infusion site pain
Multiple allergies (allergy to multiple agents)
Rash

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 12 people, 30.77%
Humoral Immune Defect (impairment of humoral immunity): 5 people, 12.82%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 3 people, 7.69%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 7.69%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 7.69%
Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 3 people, 7.69%
Immune System Disorder: 3 people, 7.69%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 5.13%
Multiple Myeloma (cancer of the plasma cells): 2 people, 5.13%
Drowsiness: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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