Mestinon and Wellbutrin xl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mestinon (pyridostigmine bromide) and Wellbutrin xl (bupropion hydrochloride). Common drug interactions include hypokalaemia among females and cervical vertebral fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Mestinon and Wellbutrin xl. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Mestinon?

Mestinon has active ingredients of pyridostigmine bromide. It is often used in myasthenia gravis. eHealthMe is studying from 5,948 Mestinon users. Check the latest studies of Mestinon.

What is Wellbutrin xl?

Wellbutrin xl has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 22,996 Wellbutrin xl users. Check the latest studies of Wellbutrin xl.

On Jul, 06, 2026

27 people who take Mestinon and Wellbutrin xl together, and have interactions are studied.

Mestinon and Wellbutrin xl drug interactions.

What are the common drug interactions of Mestinon and Wellbutrin Xl, by gender? *:

female:

Hypokalaemia (low potassium)
Leukocytosis (increased white blood cells)
Melaena (the passage of black, tarry stools)
Thrombocytopenia (decrease of platelets in blood)
Abdominal pain upper
Myasthenic syndrome (a group of conditions characterized by muscle weakness (myasthenia) that worsens with physical exertion)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
White blood cell count increased
Peripheral swelling
Pyrexia (fever)

male:

Cervical vertebral fracture
Fall
Thoracic vertebral fracture

What are the common drug interactions of Mestinon and Wellbutrin Xl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Pain
Abdominal pain upper
Nausea (feeling of having an urge to vomit)

40-49:

n/a

50-59:

Cystitis (inflammation of the wall of the bladder)
Sepsis (a severe blood infection that can lead to organ failure and death)
Upper respiratory tract infection

60+:

Anaemia (lack of blood)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Procedural pain
Thrombocytopenia (decrease of platelets in blood)
Gastrointestinal stoma complication (complication of an opening surgically made in digestive tract)
Pulmonary sepsis (pus in lungs)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
White blood cell count decreased
White blood cell count increased
Fall

What are the existing conditions these people have? *

Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 12 people, 44.44%
Small Cell Lung Cancer Limited Stage (small cell lung cancer that has not spread to other body parts): 6 people, 22.22%
Stress And Anxiety: 4 people, 14.81%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 14.81%
Parkinson's Disease: 3 people, 11.11%
Pain: 3 people, 11.11%
Itching: 3 people, 11.11%
Iron Deficiency Anaemia: 3 people, 11.11%
Heavy Or Prolong Menstrual Bleeding: 3 people, 11.11%
Pneumonia: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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