Metadate cd and Protonix drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Metadate cd (methylphenidate hydrochloride) and Protonix (pantoprazole sodium). Common drug interactions include paronychia among females and diabetes mellitus among males.
The phase IV clinical study analyzes what interactions people have when they take Metadate cd and Protonix. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Metadate cd?
Metadate cd has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 646 Metadate cd users. Check the latest studies of Metadate cd.
What is Protonix?
Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.
11 people who take Metadate cd and Protonix together, and have interactions are studied.

What are the common drug interactions of Metadate Cd and Protonix, by gender? *:
female:
- Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Arthropathy
- Fatigue (feeling of tiredness)
- Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
- Headache (pain in head)
- Pain in extremity
- Abdominal distension
- Anxiety
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
male:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Neuropathy peripheral (surface nerve damage)
- Suicidal ideation
- Type 2 diabetes mellitus
What are the common drug interactions of Metadate Cd and Protonix, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Device dislocation
- Procedural haemorrhage (procedural bleeding)
- Vulvovaginal discomfort
20-29:
n/a
30-39:
n/a
40-49:
- Eye disorder
- Surgery
- Vitamin d decreased
50-59:
- Drug ineffective
- Gallbladder non-functioning
- Pain
- Abdominal discomfort
- Abdominal distension
- Anxiety
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Constipation
60+:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Neuropathy peripheral (surface nerve damage)
- Suicidal ideation
- Type 2 diabetes mellitus
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 36.36%
- Breast Cancer Metastatic: 3 people, 27.27%
- Wheezing (a high-pitched whistling sound made while you breath): 1 person, 9.09%
- Pain: 1 person, 9.09%
- Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 1 person, 9.09%
- Menopause (end of monthly cycles in women): 1 person, 9.09%
- Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 9.09%
- Depression: 1 person, 9.09%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 9.09%
- Birth Control: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Metadate cd and Protonix?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Metadate cd (646 reports)
- Protonix (132,658 reports)
Browse all drug interactions of Metadate cd and Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Metadate cd:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Metadate cd and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Protonix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on methylphenidate hydrochloride and pantoprazole sodium (the active ingredients of Metadate cd and Protonix, respectively), and Metadate cd and Protonix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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