Methadose and Olanzapine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methadose (methadone hydrochloride) and Olanzapine (olanzapine). Common drug interactions include abdominal discomfort among females and drug withdrawal syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Methadose and Olanzapine. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Methadose?

Methadose has active ingredients of methadone hydrochloride. It is often used in pain. eHealthMe is studying from 5,101 Methadose users. Check the latest studies of Methadose.

What is Olanzapine?

Olanzapine has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 69,242 Olanzapine users. Check the latest studies of Olanzapine.

On Jul, 13, 2026

30 people who take Methadose and Olanzapine together, and have interactions are studied.

Methadose and Olanzapine drug interactions.

What are the common drug interactions of Methadose and Olanzapine, by gender? *:

female:

Abdominal discomfort
Alopecia (absence of hair from areas of the body)
Amputation
Arthralgia (joint pain)
Asthenia (weakness)
Blood pressure increased
C-reactive protein increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depressed level of consciousness
Double stranded dna antibody positive

male:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Agitation (state of anxiety or nervous excitement)
Pneumonia
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Drug level above therapeutic
Electrocardiogram qt corrected interval prolonged
Neurological symptom (symptoms of nervous system disease)
Electrocardiogram qt prolonged
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Methadose and Olanzapine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Overdose

20-29:

Abdominal discomfort
Alopecia (absence of hair from areas of the body)
Amputation
Arthralgia (joint pain)
Asthenia (weakness)
Blood pressure increased
C-reactive protein increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Double stranded dna antibody positive
Drug ineffective

30-39:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Agitation (state of anxiety or nervous excitement)
Electrocardiogram qt prolonged
Nausea (feeling of having an urge to vomit)
Syncope (loss of consciousness with an inability to maintain postural tone)
Substance-induced psychotic disorder
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Anoxic encephalopathy (brain damage due to lack of oxygen)
Cardiac arrest
Pneumonia

40-49:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Somnolence (a state of near-sleep, a strong desire for sleep)
Depressed level of consciousness
Dysarthria (speech disorder)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Overdose

50-59:

Cardiac arrest
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Completed suicide (act of taking one's own life)

60+:

n/a

What are the existing conditions these people have? *

Depression: 7 people, 23.33%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 7 people, 23.33%
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 4 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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