Methocarbamol and Austedo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methocarbamol (methocarbamol) and Austedo (deutetrabenazine). Common drug interactions include confusional state among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Methocarbamol and Austedo. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Methocarbamol?

Methocarbamol has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 17,766 Methocarbamol users. Check the latest studies of Methocarbamol.

What is Austedo?

Austedo has active ingredients of deutetrabenazine. eHealthMe is studying from 4,141 Austedo users. Check the latest studies of Austedo.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

12 people who take Methocarbamol and Austedo together, and have interactions are studied.

Methocarbamol and Austedo drug interactions.

What are the common drug interactions of Methocarbamol and Austedo, by gender? *:

female:

Confusional state
Affective disorder (mental disorder)
Agitation (state of anxiety or nervous excitement)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Eye infection
Irritability
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Oral herpes (viral infection of mouth)

male:

Abdominal discomfort
Adhesion
Hypoaesthesia (reduced sense of touch or sensation)
Impaired healing
Infection
Nausea (feeling of having an urge to vomit)
Restless legs syndrome (a powerful urge to move your legs)
Salivary hypersecretion (excess saliva secretion)
Somnolence (a state of near-sleep, a strong desire for sleep)
Suicide attempt

What are the common drug interactions of Methocarbamol and Austedo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cerebrospinal fluid leakage
Headache (pain in head)

40-49:

Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug hypersensitivity

50-59:

Abdominal discomfort
Adhesion
Agitation (state of anxiety or nervous excitement)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chronic kidney disease
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diarrhoea
Dizziness
Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)

60+:

Confusional state
Affective disorder (mental disorder)
Dizziness
Lichen sclerosus (a skin disorder that causes the skin to become thin, whitened, wrinkled, and can cause itching and pain)
Oral discomfort (pain or irritation in mouth)
Agitation (state of anxiety or nervous excitement)
Irritability
Ankle fracture
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain

What are the existing conditions these people have? *

Tardive Dyskinesia (a disorder that involves involuntary movements): 8 people, 66.67%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 16.67%
Depression: 1 person, 8.33%
Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 1 person, 8.33%
Cardiac Disorder: 1 person, 8.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 8.33%
Chest Pain: 1 person, 8.33%
Constipation: 1 person, 8.33%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 8.33%
Drowsiness: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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