Methocarbamol and Simponi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methocarbamol (methocarbamol) and Simponi (golimumab). Common drug interactions include obstruction among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Methocarbamol and Simponi. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Methocarbamol?

Methocarbamol has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 17,766 Methocarbamol users. Check the latest studies of Methocarbamol.

What is Simponi?

Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.

On Jul, 27, 2026

38 people who take Methocarbamol and Simponi together, and have interactions are studied.

Methocarbamol and Simponi drug interactions.

What are the common drug interactions of Methocarbamol and Simponi, by gender? *:

female:

Obstruction
Abscess (pus)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diarrhoea
Nausea (feeling of having an urge to vomit)
Peripheral swelling
Psoriasis (immune-mediated disease that affects the skin)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Staphylococcal infection (an infection with staphylococcus bacteria)
Allergy to animal

male:

Drug ineffective
Synovitis (inflammation of the synovial membrane)
Body temperature increased
Drug effect decreased
Influenza
Lethargy (tiredness)
Pruritus (severe itching of the skin)

What are the common drug interactions of Methocarbamol and Simponi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diarrhoea
Dyspepsia (indigestion)
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Vomiting

40-49:

Anaphylactic reaction (serious allergic reaction)
Body temperature increased
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Influenza
Lethargy (tiredness)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Peripheral swelling
Psoriasis (immune-mediated disease that affects the skin)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)

50-59:

Surgery
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Fatigue (feeling of tiredness)
Heart rate decreased
Hypotension (abnormally low blood pressure)

60+:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Limb injury
Hospitalisation
Memory impairment
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Pneumonia
Pyrexia (fever)
Synovitis (inflammation of the synovial membrane)
Weight decreased
Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the existing conditions these people have? *

Ankylosing Spondylitis (type of arthritis affecting the spine): 7 people, 18.42%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 4 people, 10.53%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 10.53%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.89%
Inflammation: 3 people, 7.89%
Indigestion: 3 people, 7.89%
Pustular Psoriasis (raised bumps on the skin that are filled with pus): 2 people, 5.26%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 5.26%
Pain: 2 people, 5.26%
High Blood Pressure: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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