Methocarbamol and Tagamet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methocarbamol (methocarbamol) and Tagamet (cimetidine). Common drug interactions include renal failure among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Methocarbamol and Tagamet. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Methocarbamol?

Methocarbamol has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 17,766 Methocarbamol users. Check the latest studies of Methocarbamol.

What is Tagamet?

Tagamet has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,011 Tagamet users. Check the latest studies of Tagamet.

On Jul, 12, 2026

40 people who take Methocarbamol and Tagamet together, and have interactions are studied.

Methocarbamol and Tagamet drug interactions.

What are the common drug interactions of Methocarbamol and Tagamet, by gender? *:

female:

Renal failure (kidney dysfunction)
Depression
Anxiety
Bone disorder
Fall
Osteoporosis (bones weak and more likely to break)
Nephrogenic anaemia (anaemia due to kidney disease)
Suicidal ideation
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Glomerulonephritis minimal lesion (a disease of the kidney that causes nephrotic syndrome and usually affects children)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Death
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)

What are the common drug interactions of Methocarbamol and Tagamet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Fall
Foot fracture
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nephrogenic anaemia (anaemia due to kidney disease)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteoporosis (bones weak and more likely to break)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Spinal fracture (fracture in one of vertebrae)
Thoracic vertebral fracture

40-49:

Renal failure (kidney dysfunction)
Anxiety
Chronic kidney disease
Depression
Suicidal ideation
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal injury (kidney injury)
Drug abuse
Mania (a state of abnormally elevated or irritable mood)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Fall
Abnormal behaviour
Anxiety
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Balance disorder

60+:

Chronic kidney disease
Glomerulonephritis minimal lesion (a disease of the kidney that causes nephrotic syndrome and usually affects children)
Cardiovascular disorder (heart diseases)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Foot fracture
Liver injury
Lumbar radiculopathy (radicular pain in the low back and legs)
Multiple fractures

What are the existing conditions these people have? *

Pain: 22 people, 55.00%
High Blood Cholesterol: 17 people, 42.50%
High Blood Pressure: 16 people, 40.00%
Depression: 16 people, 40.00%
Stress And Anxiety: 11 people, 27.50%
Infection: 11 people, 27.50%
Neuralgia (pain in one or more nerves): 10 people, 25.00%
Fluid Retention (an abnormal accumulation of fluid in the blood): 9 people, 22.50%
Headache (pain in head): 8 people, 20.00%
Nausea (feeling of having an urge to vomit): 7 people, 17.50%

* Approximation only. Some reports may have incomplete information.

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