Methotrexate sodium and Lamisil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methotrexate sodium (methotrexate sodium) and Lamisil (terbinafine hydrochloride). Common drug interactions include diarrhoea among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Methotrexate sodium and Lamisil. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Methotrexate sodium?

Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 97,680 Methotrexate sodium users. Check the latest studies of Methotrexate sodium.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.



On Aug, 06, 2026

21 people who take Methotrexate sodium and Lamisil together, and have interactions are studied.

Methotrexate sodium and Lamisil drug interactions.

What are the common drug interactions of Methotrexate Sodium and Lamisil, by gender? *:

female:

  1. Diarrhoea
  2. Vomiting
  3. Back pain
  4. Pain in extremity
  5. Peripheral swelling
  6. Weight decreased
  7. Heart rate increased
  8. Arthralgia (joint pain)
  9. Arthropathy
  10. Heart rate decreased

male:

  1. Abdominal distension
  2. Abdominal pain
  3. Skin disorder (skin disease)
  4. Tinea pedis (a contagious skin infection caused by the ringworm fungus)
  5. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  6. Ascites (accumulation of fluid in the abdominal cavity)
  7. Hepatic lesion
  8. Hepatocellular carcinoma (liver cancer)
  9. Drug ineffective
  10. Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Methotrexate Sodium and Lamisil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Drug ineffective
  2. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  3. Skin disorder (skin disease)

50-59:

  1. Calculus urinary (stone in urinary system)
  2. Drug hypersensitivity
  3. Pyrexia (fever)

60+:

  1. Diarrhoea
  2. Vomiting
  3. Heart rate decreased
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  5. Anaemia (lack of blood)
  6. Asthenia (weakness)
  7. Bell's palsy (facial paralysis)
  8. Bladder disorder
  9. Blood pressure diastolic decreased
  10. Blood pressure diastolic increased

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 7 people, 33.33%
  2. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 6 people, 28.57%
  3. Urinary Tract Infection: 5 people, 23.81%
  4. Fungal Infection: 5 people, 23.81%
  5. Anaemia (lack of blood): 5 people, 23.81%
  6. Rashes (redness): 2 people, 9.52%
  7. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Methotrexate sodium and Lamisil?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Methotrexate sodium and Lamisil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methotrexate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lamisil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methotrexate sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lamisil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on methotrexate sodium and terbinafine hydrochloride (the active ingredients of Methotrexate sodium and Lamisil, respectively), and Methotrexate sodium and Lamisil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: