Methylcobalamin and Olopatadine hydrochloride drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Methylcobalamin (vitamin b12) and Olopatadine hydrochloride (olopatadine hydrochloride). Common drug interactions include alanine aminotransferase increased among females and gait disturbance among males.
The phase IV clinical study analyzes what interactions people have when they take Methylcobalamin and Olopatadine hydrochloride. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Methylcobalamin?
Methylcobalamin has active ingredients of vitamin b12. It is often used in vitamin b12 deficiency. eHealthMe is studying from 3,184 Methylcobalamin users. Check the latest studies of Methylcobalamin.
What is Olopatadine hydrochloride?
Olopatadine hydrochloride has active ingredients of olopatadine hydrochloride. eHealthMe is studying from 4,420 Olopatadine hydrochloride users. Check the latest studies of Olopatadine hydrochloride.
22 people who take Methylcobalamin and Olopatadine hydrochloride together, and have interactions are studied.

What are the common drug interactions of Methylcobalamin and Olopatadine Hydrochloride, by gender? *:
female:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Urinary tract infection
- Burning sensation
- Decreased appetite
- Dizziness
- Hypoaesthesia (reduced sense of touch or sensation)
- Ligament sprain (ligament stretched)
- Lymphocyte count decreased
- Nausea (feeling of having an urge to vomit)
male:
- Gait disturbance
- Interstitial lung disease
- Gastric cancer (stomach cancer)
- Pemphigoid (tense blisters on the skin)
- Altered state of consciousness (altered state of mind)
- Blood pressure increased
- Cardiac failure
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
What are the common drug interactions of Methylcobalamin and Olopatadine Hydrochloride, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Bacteraemia (presence of bacteria in the blood)
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Endocarditis (inflammation in heart muscle)
- Liver disorder (liver diseases)
- Mycoplasma test positive
- Pelvic venous thrombosis (blood clot occurring inside a blood vessel and thromboses (dvts) that form in the deep veins of the legs or in the pelvic veins)
- Splenic infarction (tissue damage of spleen)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Transfusion-related acute lung injury (lung injury due to blood transfusion)
30-39:
n/a
40-49:
- Depressed level of consciousness
- Headache (pain in head)
- Subdural haematoma (blood collects between the skull and the surface of the brain)
50-59:
- Urinary tract infection
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Burning sensation
- Dizziness
- Hypoaesthesia (reduced sense of touch or sensation)
- Ligament sprain (ligament stretched)
- Lymphocyte count decreased
- Nausea (feeling of having an urge to vomit)
- Post herpetic neuralgia (neuralgia caused by the varicella zoster virus)
60+:
- Decreased appetite
- Platelet count decreased
- Gamma-glutamyltransferase increased
- Interstitial lung disease
- Liver disorder (liver diseases)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Weight increased
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Altered state of consciousness (altered state of mind)
- Blood pressure increased
What are the existing conditions these people have? *
- Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 4 people, 18.18%
- Liver Disorder (liver diseases): 4 people, 18.18%
- Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 4 people, 18.18%
- High Blood Pressure: 3 people, 13.64%
- Febrile Neutropenia (fever with reduced white blood cells): 3 people, 13.64%
- Small Cell Lung Cancer Extensive Stage (small cell lung cancer that has spread (metastasized) to other regions of the body such as another lobe of the lung or the brain): 2 people, 9.09%
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 2 people, 9.09%
- Cataract (clouding of the lens inside the eye): 2 people, 9.09%
- Constipation: 2 people, 9.09%
- Dental Caries: 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Methylcobalamin and Olopatadine hydrochloride?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Methylcobalamin (3,184 reports)
- Olopatadine hydrochloride (4,420 reports)
Browse all drug interactions of Methylcobalamin and Olopatadine hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Methylcobalamin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Olopatadine hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methylcobalamin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Olopatadine hydrochloride and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on vitamin b12 and olopatadine hydrochloride (the active ingredients of Methylcobalamin and Olopatadine hydrochloride, respectively), and Methylcobalamin and Olopatadine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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