Methyldopa and Catapres drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methyldopa (methyldopa) and Catapres (clonidine hydrochloride). Common drug interactions include anaemia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Methyldopa and Catapres. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Methyldopa?

Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.

What is Catapres?

Catapres has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,680 Catapres users. Check the latest studies of Catapres.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

13 people who take Methyldopa and Catapres together, and have interactions are studied.

Methyldopa and Catapres drug interactions.

What are the common drug interactions of Methyldopa and Catapres, by gender? *:

female:

  1. Anaemia (lack of blood)
  2. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  3. Lupus-like syndrome (a disease symptom matches with lupus an immune disease)
  4. Neuropathy peripheral (surface nerve damage)
  5. Premature baby
  6. Renal failure (kidney dysfunction)
  7. Asthenia (weakness)
  8. Chronic kidney disease
  9. Maternal exposure during pregnancy (use of substance during pregnancy)
  10. Nausea (feeling of having an urge to vomit)

male:

  1. Chronic kidney disease
  2. Hypertensive crisis
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Atrophy (wasting away of a part of the body)
  5. Back pain
  6. Balance disorder
  7. Confusional state
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  10. Dizziness

What are the common drug interactions of Methyldopa and Catapres, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anaemia (lack of blood)
  2. Polyhydramnios (excess of amniotic fluid in the amniotic sac)
  3. Pregnancy induced hypertension
  4. Proteinuria (presence of protein in the urine)
  5. Renal failure (kidney dysfunction)

30-39:

n/a

40-49:

  1. Autoimmune neuropathy (disease or dysfunction of one or more peripheral nerves by autoimmune disorders)
  2. Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
  3. Drug ineffective
  4. Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)

50-59:

  1. Chronic kidney disease
  2. Hypertensive crisis
  3. Renal failure (kidney dysfunction)
  4. Anaemia (lack of blood)
  5. Areflexia (absence of a reflex)
  6. Arthralgia (joint pain)
  7. Atrophy (wasting away of a part of the body)
  8. Back pain
  9. Balance disorder
  10. Confusional state

60+:

  1. Lupus-like syndrome (a disease symptom matches with lupus an immune disease)
  2. Neuropathy peripheral (surface nerve damage)
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Chronic kidney disease
  5. Renal failure (kidney dysfunction)
  6. Renal injury (kidney injury)
  7. Renal ischaemia (lack of blood supply to kidney)
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Vulvar dysplasia (vulval dysplasia means that there are cells that are no longer normal and may be trying to become a cancer)

What are the existing conditions these people have? *

  1. Pain: 3 people, 23.08%
  2. High Blood Cholesterol: 3 people, 23.08%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 23.08%
  4. Breast Cancer: 2 people, 15.38%
  5. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 2 people, 15.38%
  6. Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls): 1 person, 7.69%
  7. Depression: 1 person, 7.69%
  8. Affective Disorder (mental disorder): 1 person, 7.69%
  9. Asthma: 1 person, 7.69%
  10. Blood Glucose Decreased: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Methyldopa and Catapres?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Methyldopa and Catapres:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methyldopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Catapres:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methyldopa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Catapres and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on methyldopa and clonidine hydrochloride (the active ingredients of Methyldopa and Catapres, respectively), and Methyldopa and Catapres (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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