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Methyldopa and Naltrexone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methyldopa (methyldopa) and Naltrexone (naltrexone). Common drug interactions include diplopia among females and musculoskeletal disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Methyldopa and Naltrexone. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Methyldopa?

Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.

What is Naltrexone?

Naltrexone has active ingredients of naltrexone. eHealthMe is studying from 4,833 Naltrexone users. Check the latest studies of Naltrexone.

On Jul, 18, 2026

18 people who take Methyldopa and Naltrexone together, and have interactions are studied.

Methyldopa and Naltrexone drug interactions.

What are the common drug interactions of Methyldopa and Naltrexone, by gender? *:

female:

  1. Diplopia (double vision)
  2. Drug hypersensitivity
  3. Drug ineffective
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Dyspnoea (difficult or laboured respiration)
  6. Enteritis (inflammation of the small intestine)
  7. Epistaxis (bleed from the nose)
  8. Fatigue (feeling of tiredness)
  9. Fluid retention (an abnormal accumulation of fluid in the blood)
  10. Gastric infection (infection of stomach)

male:

  1. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  2. Pain in extremity

What are the common drug interactions of Methyldopa and Naltrexone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Diplopia (double vision)
  2. Drug hypersensitivity
  3. Drug ineffective
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Dyspnoea (difficult or laboured respiration)
  6. Enteritis (inflammation of the small intestine)
  7. Epistaxis (bleed from the nose)
  8. Fatigue (feeling of tiredness)
  9. Fluid retention (an abnormal accumulation of fluid in the blood)
  10. Gastric infection (infection of stomach)

60+:

  1. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  2. Pain in extremity

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 94.44%
  2. Pain: 17 people, 94.44%
  3. Nasal Polyps (masses that develop in the lining of the nose): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Methyldopa and Naltrexone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Methyldopa and Naltrexone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methyldopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Naltrexone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methyldopa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naltrexone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on methyldopa and naltrexone (the active ingredients of Methyldopa and Naltrexone, respectively), and Methyldopa and Naltrexone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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