Methyldopa and Rabeprazole drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Methyldopa (methyldopa) and Rabeprazole (rabeprazole sodium). Common drug interactions include impaired healing among females and foetal exposure during pregnancy among males.
The phase IV clinical study analyzes what interactions people have when they take Methyldopa and Rabeprazole. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Methyldopa?
Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.
What is Rabeprazole?
Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.
14 people who take Methyldopa and Rabeprazole together, and have interactions are studied.

What are the common drug interactions of Methyldopa and Rabeprazole, by gender? *:
female:
- Impaired healing
- Maternal exposure during pregnancy (use of substance during pregnancy)
- Pain
- Vasoplegia syndrome (low systemic vascular resistance)
- Premature delivery
- Fibula fracture
- Gestational hypertension (elevated blood pressure during pregnancy)
- Pathological fracture (broken bone caused by disease)
- Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
- General physical health deterioration (weak health status)
male:
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
- Low birth weight baby
- Premature baby
What are the common drug interactions of Methyldopa and Rabeprazole, by age (0-1 to 60+)? *:
0-1:
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
- Low birth weight baby
- Premature baby
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Maternal exposure during pregnancy (use of substance during pregnancy)
- Premature delivery
- Gestational hypertension (elevated blood pressure during pregnancy)
40-49:
n/a
50-59:
n/a
60+:
- Fibula fracture
- Pathological fracture (broken bone caused by disease)
- Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
- General physical health deterioration (weak health status)
- Hypotension (abnormally low blood pressure)
- Impaired healing
- Pain
- Vasoplegia syndrome (low systemic vascular resistance)
What are the existing conditions these people have? *
- Gestational Hypertension (elevated blood pressure during pregnancy): 8 people, 57.14%
- Nephrogenic Anaemia (anaemia due to kidney disease): 2 people, 14.29%
- Osteoporosis (bones weak and more likely to break): 1 person, 7.14%
- Labor Stimulation: 1 person, 7.14%
- Gastric Ulcer (stomach ulcer): 1 person, 7.14%
- Diabetes: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Methyldopa and Rabeprazole?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Methyldopa (6,475 reports)
- Rabeprazole (31,689 reports)
Browse all drug interactions of Methyldopa and Rabeprazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Methyldopa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rabeprazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methyldopa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rabeprazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on methyldopa and rabeprazole sodium (the active ingredients of Methyldopa and Rabeprazole, respectively), and Methyldopa and Rabeprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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